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A Combinatorial Regulatory Platform Determines Expression of RNA Polymerase III Subunit RPC7α (POLR3G) in Cancer

SIMPLE SUMMARY: The RNA polymerase III complex incorporates two forms of subunit RPC7: RPC7α, which is highly abundant during early development, and RPC7β, the constitutive form of RPC7 in most tissues. Here, we investigate the gene regulatory mechanisms that give rise to high RPC7α levels in cancer...

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Detalles Bibliográficos
Autores principales: Cheng, Ruiying, Zhou, Sihang, K C, Rajendra, Lizarazo, Simon, Mouli, Leela, Jayanth, Anshita, Liu, Qing, Van Bortle, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605170/
https://www.ncbi.nlm.nih.gov/pubmed/37894362
http://dx.doi.org/10.3390/cancers15204995

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