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A Combinatorial Regulatory Platform Determines Expression of RNA Polymerase III Subunit RPC7α (POLR3G) in Cancer
SIMPLE SUMMARY: The RNA polymerase III complex incorporates two forms of subunit RPC7: RPC7α, which is highly abundant during early development, and RPC7β, the constitutive form of RPC7 in most tissues. Here, we investigate the gene regulatory mechanisms that give rise to high RPC7α levels in cancer...
Autores principales: | Cheng, Ruiying, Zhou, Sihang, K C, Rajendra, Lizarazo, Simon, Mouli, Leela, Jayanth, Anshita, Liu, Qing, Van Bortle, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605170/ https://www.ncbi.nlm.nih.gov/pubmed/37894362 http://dx.doi.org/10.3390/cancers15204995 |
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