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Exosc9 Initiates SUMO-Dependent lncRNA TERRA Degradation to Impact Telomeric Integrity in Endocrine Therapy Insensitive Hormone Receptor-Positive Breast Cancer

Long, noncoding RNAs (lncRNAs) are indispensable for normal cell physiology and, consequently, are tightly regulated in human cells. Yet, unlike mRNA, substantially less is known about the mechanisms for lncRNA degradation. It is important to delineate the regulatory control of lncRNA degradation, p...

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Detalles Bibliográficos
Autores principales: Quttina, Maram, Waiters, Kacie D., Khan, Ashfia Fatima, Karami, Samaneh, Peidl, Anthony S., Babajide, Mariam Funmi, Pennington, Justus, Merchant, Fatima A., Bawa-Khalfe, Tasneem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605189/
https://www.ncbi.nlm.nih.gov/pubmed/37887339
http://dx.doi.org/10.3390/cells12202495