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Exploring Plant Meiosis: Insights from the Kinetochore Perspective

The central player for chromosome segregation in both mitosis and meiosis is the macromolecular kinetochore structure, which is assembled by >100 structural and regulatory proteins on centromere DNA. Kinetochores play a crucial role in cell division by connecting chromosomal DNA and microtubule p...

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Autores principales: Zhou, Kang-Di, Zhang, Cai-Xia, Niu, Fu-Rong, Bai, Hao-Chen, Wu, Dan-Dan, Deng, Jia-Cheng, Qian, Hong-Yuan, Jiang, Yun-Lei, Ma, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605258/
https://www.ncbi.nlm.nih.gov/pubmed/37886947
http://dx.doi.org/10.3390/cimb45100504
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author Zhou, Kang-Di
Zhang, Cai-Xia
Niu, Fu-Rong
Bai, Hao-Chen
Wu, Dan-Dan
Deng, Jia-Cheng
Qian, Hong-Yuan
Jiang, Yun-Lei
Ma, Wei
author_facet Zhou, Kang-Di
Zhang, Cai-Xia
Niu, Fu-Rong
Bai, Hao-Chen
Wu, Dan-Dan
Deng, Jia-Cheng
Qian, Hong-Yuan
Jiang, Yun-Lei
Ma, Wei
author_sort Zhou, Kang-Di
collection PubMed
description The central player for chromosome segregation in both mitosis and meiosis is the macromolecular kinetochore structure, which is assembled by >100 structural and regulatory proteins on centromere DNA. Kinetochores play a crucial role in cell division by connecting chromosomal DNA and microtubule polymers. This connection helps in the proper segregation and alignment of chromosomes. Additionally, kinetochores can act as a signaling hub, regulating the start of anaphase through the spindle assembly checkpoint, and controlling the movement of chromosomes during anaphase. However, the role of various kinetochore proteins in plant meiosis has only been recently elucidated, and these proteins differ in their functionality from those found in animals. In this review, our current knowledge of the functioning of plant kinetochore proteins in meiosis will be summarized. In addition, the functional similarities and differences of core kinetochore proteins in meiosis between plants and other species are discussed, and the potential applications of manipulating certain kinetochore genes in meiosis for breeding purposes are explored.
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spelling pubmed-106052582023-10-28 Exploring Plant Meiosis: Insights from the Kinetochore Perspective Zhou, Kang-Di Zhang, Cai-Xia Niu, Fu-Rong Bai, Hao-Chen Wu, Dan-Dan Deng, Jia-Cheng Qian, Hong-Yuan Jiang, Yun-Lei Ma, Wei Curr Issues Mol Biol Review The central player for chromosome segregation in both mitosis and meiosis is the macromolecular kinetochore structure, which is assembled by >100 structural and regulatory proteins on centromere DNA. Kinetochores play a crucial role in cell division by connecting chromosomal DNA and microtubule polymers. This connection helps in the proper segregation and alignment of chromosomes. Additionally, kinetochores can act as a signaling hub, regulating the start of anaphase through the spindle assembly checkpoint, and controlling the movement of chromosomes during anaphase. However, the role of various kinetochore proteins in plant meiosis has only been recently elucidated, and these proteins differ in their functionality from those found in animals. In this review, our current knowledge of the functioning of plant kinetochore proteins in meiosis will be summarized. In addition, the functional similarities and differences of core kinetochore proteins in meiosis between plants and other species are discussed, and the potential applications of manipulating certain kinetochore genes in meiosis for breeding purposes are explored. MDPI 2023-09-28 /pmc/articles/PMC10605258/ /pubmed/37886947 http://dx.doi.org/10.3390/cimb45100504 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhou, Kang-Di
Zhang, Cai-Xia
Niu, Fu-Rong
Bai, Hao-Chen
Wu, Dan-Dan
Deng, Jia-Cheng
Qian, Hong-Yuan
Jiang, Yun-Lei
Ma, Wei
Exploring Plant Meiosis: Insights from the Kinetochore Perspective
title Exploring Plant Meiosis: Insights from the Kinetochore Perspective
title_full Exploring Plant Meiosis: Insights from the Kinetochore Perspective
title_fullStr Exploring Plant Meiosis: Insights from the Kinetochore Perspective
title_full_unstemmed Exploring Plant Meiosis: Insights from the Kinetochore Perspective
title_short Exploring Plant Meiosis: Insights from the Kinetochore Perspective
title_sort exploring plant meiosis: insights from the kinetochore perspective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605258/
https://www.ncbi.nlm.nih.gov/pubmed/37886947
http://dx.doi.org/10.3390/cimb45100504
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