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Characterization of Age-Associated, Neutrophil-to-Lymphocyte Ratio (NLR) and Systemic Immune-Inflammatory Index (SII) as Biomarkers of Inflammation in Geriatric Patients with Cancer Treated with Immune Checkpoint Inhibitors: Impact on Efficacy and Survival

SIMPLE SUMMARY: Older adults have a unique biology characterized by inflammation. Inflammation, however, is thought to affect the efficacy of immune therapies in patients with cancer, and there are currently no biomarkers to predict the response of older patients with cancer to immune checkpoint inh...

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Detalles Bibliográficos
Autores principales: Choucair, Khalil, Nebhan, Caroline, Cortellini, Alessio, Hentzen, Stijn, Wang, Yinghong, Liu, Cynthia, Giusti, Raffaele, Filetti, Marco, Ascierto, Paolo Antonio, Vanella, Vito, Galetta, Domenico, Catino, Annamaria, Al-Bzour, Nour, Saeed, Azhar, Cavalcante, Ludimila, Pizzutilo, Pamela, Genova, Carlo, Bersanelli, Melissa, Buti, Sebastiano, Johnson, Douglas B., Fulgenzi, Claudia Angela Maria, Pinato, David J., Radford, Maluki, Kim, Chul, Naqash, Abdul Rafeh, Saeed, Anwaar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605297/
https://www.ncbi.nlm.nih.gov/pubmed/37894419
http://dx.doi.org/10.3390/cancers15205052