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Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes

Locally advanced non-small cell lung cancer (NSCLC) consists of a heterogeneous group, with different pulmonary extension and lymph nodal involvement. Robotic surgery can play a key role in these tumours thanks to its technological features, although open surgery is still considered the gold-standar...

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Autores principales: Zirafa, Carmelina C., Romano, Gaetano, Sicolo, Elisa, Bagalà, Elena, Manfredini, Beatrice, Alì, Greta, Castaldi, Andrea, Morganti, Riccardo, Davini, Federico, Fontanini, Gabriella, Melfi, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605396/
https://www.ncbi.nlm.nih.gov/pubmed/37887558
http://dx.doi.org/10.3390/curroncol30100658
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author Zirafa, Carmelina C.
Romano, Gaetano
Sicolo, Elisa
Bagalà, Elena
Manfredini, Beatrice
Alì, Greta
Castaldi, Andrea
Morganti, Riccardo
Davini, Federico
Fontanini, Gabriella
Melfi, Franca
author_facet Zirafa, Carmelina C.
Romano, Gaetano
Sicolo, Elisa
Bagalà, Elena
Manfredini, Beatrice
Alì, Greta
Castaldi, Andrea
Morganti, Riccardo
Davini, Federico
Fontanini, Gabriella
Melfi, Franca
author_sort Zirafa, Carmelina C.
collection PubMed
description Locally advanced non-small cell lung cancer (NSCLC) consists of a heterogeneous group, with different pulmonary extension and lymph nodal involvement. Robotic surgery can play a key role in these tumours thanks to its technological features, although open surgery is still considered the gold-standard approach. Our study aims to evaluate the surgical and oncological outcomes of locally advanced NSCLC patients who underwent robotic surgery in a high-volume centre. Data from consecutive patients with locally advanced NSCLC who underwent robotic lobectomy were retrospectively analysed and compared with patients treated with open surgery. Clinical characteristics and surgical and oncological information were evaluated. From 2010 to 2020, 131 patients underwent anatomical lung resection for locally advanced NSCLC. A total of 61 patients were treated with robotic surgery (46.6%); the median hospitalization time was 5.9 days (range 2–27) and the postoperative complication rate was 18%. Open surgery was performed in 70 patients (53.4%); the median length of stay was 9 days (range 4–48) and the postoperative complication rate was 22.9%. The median follow-up time was 70 months. The 5-year overall survival was 34% in the robotic group and 31% in the thoracotomy group. Robotic surgery can be considered safe and feasible not only for early stages but also for the treatment of locally advanced NSCLC.
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spelling pubmed-106053962023-10-28 Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes Zirafa, Carmelina C. Romano, Gaetano Sicolo, Elisa Bagalà, Elena Manfredini, Beatrice Alì, Greta Castaldi, Andrea Morganti, Riccardo Davini, Federico Fontanini, Gabriella Melfi, Franca Curr Oncol Article Locally advanced non-small cell lung cancer (NSCLC) consists of a heterogeneous group, with different pulmonary extension and lymph nodal involvement. Robotic surgery can play a key role in these tumours thanks to its technological features, although open surgery is still considered the gold-standard approach. Our study aims to evaluate the surgical and oncological outcomes of locally advanced NSCLC patients who underwent robotic surgery in a high-volume centre. Data from consecutive patients with locally advanced NSCLC who underwent robotic lobectomy were retrospectively analysed and compared with patients treated with open surgery. Clinical characteristics and surgical and oncological information were evaluated. From 2010 to 2020, 131 patients underwent anatomical lung resection for locally advanced NSCLC. A total of 61 patients were treated with robotic surgery (46.6%); the median hospitalization time was 5.9 days (range 2–27) and the postoperative complication rate was 18%. Open surgery was performed in 70 patients (53.4%); the median length of stay was 9 days (range 4–48) and the postoperative complication rate was 22.9%. The median follow-up time was 70 months. The 5-year overall survival was 34% in the robotic group and 31% in the thoracotomy group. Robotic surgery can be considered safe and feasible not only for early stages but also for the treatment of locally advanced NSCLC. MDPI 2023-10-12 /pmc/articles/PMC10605396/ /pubmed/37887558 http://dx.doi.org/10.3390/curroncol30100658 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zirafa, Carmelina C.
Romano, Gaetano
Sicolo, Elisa
Bagalà, Elena
Manfredini, Beatrice
Alì, Greta
Castaldi, Andrea
Morganti, Riccardo
Davini, Federico
Fontanini, Gabriella
Melfi, Franca
Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes
title Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes
title_full Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes
title_fullStr Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes
title_full_unstemmed Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes
title_short Robotic versus Open Surgery in Locally Advanced Non-Small Cell Lung Cancer: Evaluation of Surgical and Oncological Outcomes
title_sort robotic versus open surgery in locally advanced non-small cell lung cancer: evaluation of surgical and oncological outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605396/
https://www.ncbi.nlm.nih.gov/pubmed/37887558
http://dx.doi.org/10.3390/curroncol30100658
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