Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model

BACKGROUND: Recent findings from studies of mouse models of Mendelian disorders of epigenetic machinery strongly support the potential for postnatal therapies to improve neurobehavioral and cognitive deficits. As several of these therapies move into human clinical trials, the search for biomarkers o...

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Detalles Bibliográficos
Autores principales: Goodman, Sarah Jessica, Luperchio, Teresa Romeo, Ellegood, Jacob, Chater-Diehl, Eric, Lerch, Jason P., Bjornsson, Hans Tomas, Weksberg, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605417/
https://www.ncbi.nlm.nih.gov/pubmed/37884963
http://dx.doi.org/10.1186/s13148-023-01582-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605417/
https://www.ncbi.nlm.nih.gov/pubmed/37884963
http://dx.doi.org/10.1186/s13148-023-01582-x

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