Hypothermic Protection in Neocortex Is Topographic and Laminar, Seizure Unmitigating, and Partially Rescues Neurons Depleted of RNA Splicing Protein Rbfox3/NeuN in Neonatal Hypoxic-Ischemic Male Piglets

The effects of hypothermia on neonatal encephalopathy may vary topographically and cytopathologically in the neocortex with manifestations potentially influenced by seizures that alter the severity, distribution, and type of neuropathology. We developed a neonatal piglet survival model of hypoxic-is...

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Detalles Bibliográficos
Autores principales: Primiani, Christopher T., Lee, Jennifer K., O’Brien, Caitlin E., Chen, May W., Perin, Jamie, Kulikowicz, Ewa, Santos, Polan, Adams, Shawn, Lester, Bailey, Rivera-Diaz, Natalia, Olberding, Valerie, Niedzwiecki, Mark V., Ritzl, Eva K., Habela, Christa W., Liu, Xiuyun, Yang, Zeng-Jin, Koehler, Raymond C., Martin, Lee J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605428/
https://www.ncbi.nlm.nih.gov/pubmed/37887298
http://dx.doi.org/10.3390/cells12202454

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