Cargando…
Development of New Genome Editing Tools for the Treatment of Hyperlipidemia
Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is often associated with an increased risk of cardiovascular diseases such as heart attacks and strokes. Traditional treatment approaches for hyperlipidemia involve lifestyle modifications, dietary changes,...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605581/ https://www.ncbi.nlm.nih.gov/pubmed/37887310 http://dx.doi.org/10.3390/cells12202466 |
_version_ | 1785127108263018496 |
---|---|
author | Preta, Giulio |
author_facet | Preta, Giulio |
author_sort | Preta, Giulio |
collection | PubMed |
description | Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is often associated with an increased risk of cardiovascular diseases such as heart attacks and strokes. Traditional treatment approaches for hyperlipidemia involve lifestyle modifications, dietary changes, and the use of medications like statins. Recent advancements in genome editing technologies, including CRISPR-Cas9, have opened up new possibilities for the treatment of this condition. This review provides a general overview of the main target genes involved in lipid metabolism and highlights the progress made during recent years towards the development of new treatments for dyslipidemia. |
format | Online Article Text |
id | pubmed-10605581 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106055812023-10-28 Development of New Genome Editing Tools for the Treatment of Hyperlipidemia Preta, Giulio Cells Review Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is often associated with an increased risk of cardiovascular diseases such as heart attacks and strokes. Traditional treatment approaches for hyperlipidemia involve lifestyle modifications, dietary changes, and the use of medications like statins. Recent advancements in genome editing technologies, including CRISPR-Cas9, have opened up new possibilities for the treatment of this condition. This review provides a general overview of the main target genes involved in lipid metabolism and highlights the progress made during recent years towards the development of new treatments for dyslipidemia. MDPI 2023-10-16 /pmc/articles/PMC10605581/ /pubmed/37887310 http://dx.doi.org/10.3390/cells12202466 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Preta, Giulio Development of New Genome Editing Tools for the Treatment of Hyperlipidemia |
title | Development of New Genome Editing Tools for the Treatment of Hyperlipidemia |
title_full | Development of New Genome Editing Tools for the Treatment of Hyperlipidemia |
title_fullStr | Development of New Genome Editing Tools for the Treatment of Hyperlipidemia |
title_full_unstemmed | Development of New Genome Editing Tools for the Treatment of Hyperlipidemia |
title_short | Development of New Genome Editing Tools for the Treatment of Hyperlipidemia |
title_sort | development of new genome editing tools for the treatment of hyperlipidemia |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605581/ https://www.ncbi.nlm.nih.gov/pubmed/37887310 http://dx.doi.org/10.3390/cells12202466 |
work_keys_str_mv | AT pretagiulio developmentofnewgenomeeditingtoolsforthetreatmentofhyperlipidemia |