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Development of New Genome Editing Tools for the Treatment of Hyperlipidemia

Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is often associated with an increased risk of cardiovascular diseases such as heart attacks and strokes. Traditional treatment approaches for hyperlipidemia involve lifestyle modifications, dietary changes,...

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Detalles Bibliográficos
Autor principal: Preta, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605581/
https://www.ncbi.nlm.nih.gov/pubmed/37887310
http://dx.doi.org/10.3390/cells12202466
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author Preta, Giulio
author_facet Preta, Giulio
author_sort Preta, Giulio
collection PubMed
description Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is often associated with an increased risk of cardiovascular diseases such as heart attacks and strokes. Traditional treatment approaches for hyperlipidemia involve lifestyle modifications, dietary changes, and the use of medications like statins. Recent advancements in genome editing technologies, including CRISPR-Cas9, have opened up new possibilities for the treatment of this condition. This review provides a general overview of the main target genes involved in lipid metabolism and highlights the progress made during recent years towards the development of new treatments for dyslipidemia.
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spelling pubmed-106055812023-10-28 Development of New Genome Editing Tools for the Treatment of Hyperlipidemia Preta, Giulio Cells Review Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is often associated with an increased risk of cardiovascular diseases such as heart attacks and strokes. Traditional treatment approaches for hyperlipidemia involve lifestyle modifications, dietary changes, and the use of medications like statins. Recent advancements in genome editing technologies, including CRISPR-Cas9, have opened up new possibilities for the treatment of this condition. This review provides a general overview of the main target genes involved in lipid metabolism and highlights the progress made during recent years towards the development of new treatments for dyslipidemia. MDPI 2023-10-16 /pmc/articles/PMC10605581/ /pubmed/37887310 http://dx.doi.org/10.3390/cells12202466 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Preta, Giulio
Development of New Genome Editing Tools for the Treatment of Hyperlipidemia
title Development of New Genome Editing Tools for the Treatment of Hyperlipidemia
title_full Development of New Genome Editing Tools for the Treatment of Hyperlipidemia
title_fullStr Development of New Genome Editing Tools for the Treatment of Hyperlipidemia
title_full_unstemmed Development of New Genome Editing Tools for the Treatment of Hyperlipidemia
title_short Development of New Genome Editing Tools for the Treatment of Hyperlipidemia
title_sort development of new genome editing tools for the treatment of hyperlipidemia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605581/
https://www.ncbi.nlm.nih.gov/pubmed/37887310
http://dx.doi.org/10.3390/cells12202466
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