Cargando…

Inactivation of Tumor Suppressor CYLD Inhibits Fibroblast Reprogramming to Pluripotency

SIMPLE SUMMARY: Many aspects of the regulatory mechanisms of somatic cell reprogramming—the conversion of any cell type into pluripotent stem cells—still remain elusive. The tumor suppressor CYLD regulates several signaling pathways involved in this process. However, its potential role in reprogramm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bekas, Nikolaos, Samiotaki, Martina, Papathanasiou, Maria, Mokos, Panagiotis, Pseftogas, Athanasios, Xanthopoulos, Konstantinos, Thanos, Dimitris, Mosialos, George, Dafou, Dimitra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605754/ https://www.ncbi.nlm.nih.gov/pubmed/37894364 http://dx.doi.org/10.3390/cancers15204997

Ejemplares similares

The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGFβ Signaling
por: Pseftogas, Athanasios, et al.
Publicado: (2020)

Truncation of the Deubiquitinating Domain of CYLD in Myelomonocytic Cells Attenuates Inflammatory Responses
por: Tsagaratou, Ageliki, et al.
Publicado: (2011)

P1225: CYLD, A NOVEL REGULATOR OF SPLENIC MARGINAL ZONE LYMPHOMA PATHOGENESIS
por: Pseftogkas, Athanasios, et al.
Publicado: (2023)

A Systematic Review of Common and Brain-Disease-Specific RNA Editing Alterations Providing Novel Insights into Neurological and Neurodegenerative Disease Manifestations
por: Karagianni, Korina, et al.
Publicado: (2022)

UBE2T promotes β‐catenin nuclear translocation in hepatocellular carcinoma through MAPK/ERK‐dependent activation
por: Lioulia, Elisavet, et al.
Publicado: (2022)

RNA Editing Alterations Define Disease Manifestations in the Progression of Experimental Autoimmune Encephalomyelitis (EAE)
por: Dafou, Dimitra, et al.
Publicado: (2022)

Tumor Suppressor Function of CYLD in Nonmelanoma Skin Cancer
por: Masoumi, K. C., et al.
Publicado: (2011)

Photo-Fenton and TiO(2) Photocatalytic Inactivation of Model Microorganisms under UV-A; Comparative Efficacy and Optimization
por: Kanata, Eirini, et al.
Publicado: (2023)

Functional analysis of the C. elegans cyld-1 gene reveals extensive similarity with its human homolog
por: Hadweh, Paul, et al.
Publicado: (2018)

Potential role for the tumor suppressor CYLD in brain and notochord development
por: Li, Te, et al.
Publicado: (2021)

Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD
por: Hövelmeyer, Nadine, et al.
Publicado: (2007)

The tumour suppressor CYLD regulates the p53 DNA damage response
por: Fernández-Majada, Vanesa, et al.
Publicado: (2016)

RNA editing alterations define manifestation of prion diseases
por: Kanata, Eirini, et al.
Publicado: (2019)

Application of antibody phage display to identify potential antigenic neural precursor cell proteins
por: Paspaltsis, Ioannis, et al.
Publicado: (2020)

CYLD in health and disease
por: Marín-Rubio, José L., et al.
Publicado: (2023)

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
por: Elliott, Paul R., et al.
Publicado: (2016)

Tumor suppressors inhibit reprogramming of African spiny mouse ( Acomys) fibroblasts to induced pluripotent stem cells
por: Sandoval, Aaron Gabriel W., et al.
Publicado: (2022)

Loss of Tumor Suppressor CYLD Expression Triggers Cisplatin Resistance in Oral Squamous Cell Carcinoma
por: Suenaga, Naoki, et al.
Publicado: (2019)

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes
por: Kupka, Sebastian, et al.
Publicado: (2016)

Bisdemethoxycurcumin Inhibits Hepatocellular Carcinoma Proliferation Through Akt Inactivation via CYLD-Mediated Deubiquitination
por: Qiu, Chengjiang, et al.
Publicado: (2020)

CYLD and SUMO in neuroblastoma therapy
por: Masoumi, Katarzyna Chmielarska, et al.
Publicado: (2016)

HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice
por: Afaloniati, Hara, et al.
Publicado: (2020)

CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin
por: Wickström, Sara A, et al.
Publicado: (2010)

A novel large deletion of the CYLD gene causes CYLD cutaneous syndrome in a Chinese family
por: Zhu, Ruizheng, et al.
Publicado: (2020)

Gene targeting in amyotrophic lateral sclerosis using causality-based feature selection and machine learning
por: Founta, Kyriaki, et al.
Publicado: (2023)

Role of tumor suppressor genes in the cancer-associated reprogramming of human induced pluripotent stem cells
por: Lin, Ying-Chu, et al.
Publicado: (2014)

CYLD tumour supressor regulates ciligenesis
por: Eguether, T, et al.
Publicado: (2012)

Histone Deacetylase Inhibitors in Cell Pluripotency, Differentiation, and Reprogramming
por: Kretsovali, Androniki, et al.
Publicado: (2012)

MicroRNA Alterations in the Brain and Body Fluids of Humans and Animal Prion Disease Models: Current Status and Perspectives
por: Kanata, Eirini, et al.
Publicado: (2018)

Profiling Microglia through Single-Cell RNA Sequencing over the Course of Development, Aging, and Disease
por: Pettas, Spyros, et al.
Publicado: (2022)

The Tumor Suppressor CYLD Interacts with TRIP and Regulates Negatively Nuclear Factor κB Activation by Tumor Necrosis Factor
por: Regamey, Alexandre, et al.
Publicado: (2003)

UVB radiation represses CYLD expression in melanocytes
por: Kuphal, Silke, et al.
Publicado: (2017)

The cylindromatosis (CYLD) gene and head and neck tumorigenesis
por: Verhoeft, Krista Roberta, et al.
Publicado: (2016)

Genetic Testing in CYLD Cutaneous Syndrome: An Update
por: Nagy, Nikoletta, et al.
Publicado: (2021)

Gynaecological cylindroma in association with CYLD gene mutation
por: Khoury, Emma, et al.
Publicado: (2022)

Genotoxicity-Stimulated and CYLD-Driven Malignant Transformation
por: Erol, Adnan
Publicado: (2022)

The Tumour Suppressor CYLD Is Required for Clathrin-Mediated Endocytosis of EGFR and Cetuximab-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma
por: Liu, Rin, et al.
Publicado: (2021)

Modeling human brain rhabdoid tumor by inactivating tumor suppressor genes in induced pluripotent stem cells
por: Hua, Timothy, et al.
Publicado: (2023)

Molecular mechanisms of pluripotency and reprogramming
por: Na, Jie, et al.
Publicado: (2010)

Linking Pluripotency Reprogramming and Cancer
por: Iglesias, Juan Manuel, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2496jdsj2hdacid6r18hai80tm