Runx3 Restoration Regresses K-Ras-Activated Mouse Lung Cancers and Inhibits Recurrence

Oncogenic K-RAS mutations occur in approximately 25% of human lung cancers and are most frequently found in codon 12 (G12C, G12V, and G12D). Mutated K-RAS inhibitors have shown beneficial results in many patients; however, the inhibitors specifically target K-RAS(G12C) and acquired resistance is a c...

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Detalles Bibliográficos
Autores principales: Lee, Ja-Yeol, Lee, Jung-Won, Park, Tae-Geun, Han, Sang-Hyun, Yoo, Seo-Yeong, Jung, Kyoung-Mi, Kim, Da-Mi, Lee, Ok-Jun, Kim, Dohun, Chi, Xin-Zi, Kim, Eung-Gook, Lee, You-Soub, Bae, Suk-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605764/
https://www.ncbi.nlm.nih.gov/pubmed/37887282
http://dx.doi.org/10.3390/cells12202438

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