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Digital Spatial Profiling Identifies the Tumor Periphery as a Highly Active Biological Niche in Clear Cell Renal Cell Carcinoma
SIMPLE SUMMARY: Clear cell renal cell carcinoma is characterized by a high degree of genomic intratumoral heterogeneity. The extent of spatial and functional heterogeneity, however, is much less understood. In the present study, digital spatial profiling identified the tumor periphery as a highly ac...
Autores principales: | Schneider, Felix, Kaczorowski, Adam, Jurcic, Christina, Kirchner, Martina, Schwab, Constantin, Schütz, Viktoria, Görtz, Magdalena, Zschäbitz, Stefanie, Jäger, Dirk, Stenzinger, Albrecht, Hohenfellner, Markus, Duensing, Stefan, Duensing, Anette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605891/ https://www.ncbi.nlm.nih.gov/pubmed/37894418 http://dx.doi.org/10.3390/cancers15205050 |
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