Deletions of CDKN2A and MTAP Detected by Copy-Number Variation Array Are Associated with Loss of p16 and MTAP Protein in Pleural Mesothelioma

SIMPLE SUMMARY: Loss of the CDKN2A gene and its protein p16 is a common event in pleural mesothelioma, which is frequently investigated to confirm the diagnosis. The loss of CDKN2A is often accompanied by simultaneous loss of the genes located in the vicinity, including the MTAP gene and protein. De...

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Autores principales: Vrugt, Bart, Kirschner, Michaela B., Meerang, Mayura, Oehl, Kathrin, Wagner, Ulrich, Soltermann, Alex, Moch, Holger, Opitz, Isabelle, Wild, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605896/
https://www.ncbi.nlm.nih.gov/pubmed/37894345
http://dx.doi.org/10.3390/cancers15204978

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