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The IGF-Independent Role of IRS-2 in the Secretion of MMP-9 Enhances the Growth of Prostate Carcinoma Cell Line PC3

Insulin receptor substrate-2 (IRS-2), a substrate of the insulin-like growth factor (IGF)-I receptor, is highly expressed in the prostate cancer cell line, PC3. We recently demonstrated that extracellular signal-regulated kinase (Erk1/2), a kinase downstream of IGF signaling, is activated in PC3 cel...

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Detalles Bibliográficos
Autores principales:	Furuta, Haruka, Sheng, Yina, Takahashi, Ayaka, Nagano, Raku, Kataoka, Naoyuki, Perks, Claire Marie, Barker, Rachel, Hakuno, Fumihiko, Takahashi, Shin-Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606031/ https://www.ncbi.nlm.nih.gov/pubmed/37894751 http://dx.doi.org/10.3390/ijms242015065

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