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2-Aminothiazole-Flavonoid Hybrid Derivatives Binding to Tau Protein and Responsible for Antitumor Activity in Glioblastoma

Tau protein has been described for several decades as a promoter of tubulin assembly into microtubules. Dysregulation or alterations in Tau expression have been related to various brain cancers, including the highly aggressive and lethal brain tumor glioblastoma multiform (GBM). In this respect, Tau...

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Detalles Bibliográficos
Autores principales: Hedna, Rayane, DiMaio, Attilio, Robin, Maxime, Allegro, Diane, Tatoni, Mario, Peyrot, Vincent, Barbier, Pascale, Kovacic, Hervé, Breuzard, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606064/
https://www.ncbi.nlm.nih.gov/pubmed/37894731
http://dx.doi.org/10.3390/ijms242015050