Enhanced Computed Tomography and (18)F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma

Histiocytic sarcoma (HS) is an extremely rare and aggressive malignant neoplasm of hematopoietic origin that shows morphologic and immunophenotypic evidence of histiocytic differentiation. In approximately 25% of the cases, presumed transdifferentiation of a preexisting hematolymphoid disorder can b...

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Autores principales: Cheon, Miju, Yoo, Jang, Kim, Hae Su, Lee, Miji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606069/
https://www.ncbi.nlm.nih.gov/pubmed/37892010
http://dx.doi.org/10.3390/diagnostics13203189
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author Cheon, Miju
Yoo, Jang
Kim, Hae Su
Lee, Miji
author_facet Cheon, Miju
Yoo, Jang
Kim, Hae Su
Lee, Miji
author_sort Cheon, Miju
collection PubMed
description Histiocytic sarcoma (HS) is an extremely rare and aggressive malignant neoplasm of hematopoietic origin that shows morphologic and immunophenotypic evidence of histiocytic differentiation. In approximately 25% of the cases, presumed transdifferentiation of a preexisting hematolymphoid disorder can be demonstrated. Various extranodal sites, particularly the gastrointestinal tract, soft tissue, skin, and spleen, can be involved. Enhanced CT and FDG PET/CT findings of extranodal histiocytic sarcoma have been barely reported. We present a case with extranodal HS originating in the small intestine after gastric large B-cell lymphoma, mistaken for prostate cancer metastasis in a 76-year-old man.
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spelling pubmed-106060692023-10-28 Enhanced Computed Tomography and (18)F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma Cheon, Miju Yoo, Jang Kim, Hae Su Lee, Miji Diagnostics (Basel) Interesting Images Histiocytic sarcoma (HS) is an extremely rare and aggressive malignant neoplasm of hematopoietic origin that shows morphologic and immunophenotypic evidence of histiocytic differentiation. In approximately 25% of the cases, presumed transdifferentiation of a preexisting hematolymphoid disorder can be demonstrated. Various extranodal sites, particularly the gastrointestinal tract, soft tissue, skin, and spleen, can be involved. Enhanced CT and FDG PET/CT findings of extranodal histiocytic sarcoma have been barely reported. We present a case with extranodal HS originating in the small intestine after gastric large B-cell lymphoma, mistaken for prostate cancer metastasis in a 76-year-old man. MDPI 2023-10-12 /pmc/articles/PMC10606069/ /pubmed/37892010 http://dx.doi.org/10.3390/diagnostics13203189 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Cheon, Miju
Yoo, Jang
Kim, Hae Su
Lee, Miji
Enhanced Computed Tomography and (18)F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma
title Enhanced Computed Tomography and (18)F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma
title_full Enhanced Computed Tomography and (18)F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma
title_fullStr Enhanced Computed Tomography and (18)F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma
title_full_unstemmed Enhanced Computed Tomography and (18)F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma
title_short Enhanced Computed Tomography and (18)F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma
title_sort enhanced computed tomography and (18)f-fluorodeoxyglucose positron emission tomography/computed tomography in the uncommon histiocytic sarcoma of small intestine arising after gastric large b-cell lymphoma
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606069/
https://www.ncbi.nlm.nih.gov/pubmed/37892010
http://dx.doi.org/10.3390/diagnostics13203189
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