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Lamotrigine-Loaded Poloxamer-Based Thermo-Responsive Sol–Gel: Formulation, In Vitro Assessment, Ex Vivo Permeation, and Toxicology Study

The present study aimed to prepare, characterize, and evaluate a thermo-responsive sol–gel for intranasal delivery of lamotrigine (LTG), which was designed for sustained drug delivery to treat epilepsy. LTG sol–gel was prepared using the cold method by changing the concentrations of poloxamer 407 an...

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Detalles Bibliográficos
Autores principales:	Riaz, Maria, Zaman, Muhammad, Hameed, Huma, Sarwar, Hafiz Shoaib, Khan, Mahtab Ahmad, Irfan, Ali, Shazly, Gamal A., Paiva-Santos, Ana Cláudia, Jardan, Yousef A. Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606094/ https://www.ncbi.nlm.nih.gov/pubmed/37888390 http://dx.doi.org/10.3390/gels9100817

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