Cargando…
Quantitative Assessment of Balance Function Characteristics in Older Patients with Orthostatic Hypotension
Background: Orthostatic hypotension (OH) is a common blood pressure abnormality in older adults that makes them prone to balance disorders and falls. The maintenance of balance relies on a complex regulatory system. The use of computerized dynamic posturography (CDP) can provide a quantitative evalu...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606146/ https://www.ncbi.nlm.nih.gov/pubmed/37887976 http://dx.doi.org/10.3390/geriatrics8050103 |
_version_ | 1785127246737965056 |
---|---|
author | Cui, Yao Liu, Bo Zhou, Jian Liu, Qian Ye, Hui |
author_facet | Cui, Yao Liu, Bo Zhou, Jian Liu, Qian Ye, Hui |
author_sort | Cui, Yao |
collection | PubMed |
description | Background: Orthostatic hypotension (OH) is a common blood pressure abnormality in older adults that makes them prone to balance disorders and falls. The maintenance of balance relies on a complex regulatory system. The use of computerized dynamic posturography (CDP) can provide a quantitative evaluation of balance function. The objective of this study was to utilize CDP to measure balance indicators in older individuals with OH. Methods: A total of 303 older adults were divided into an OH group of 91 and a non-OH group of 212. Various factors, including chronic diseases, medication history, laboratory tests, and balance indicators, were compared between the two groups. Results: ① Participants with OH had more chronic diseases, including coronary heart disease (p = 0.049) and a history of falls (p < 0.001), than those without OH. A history of multiple medications in the OH group was significantly more likely than in the non-OH group (p = 0.006). ② There was a significant reduction in the composite equilibrium score (SOT-COM) (p < 0.001), vision ratio score (VIS) (p < 0.001), vestibular ratio score (VEST) (p < 0.001), and directional control (DCL) (p = 0.028) in the OH group. ③ A logistic regression analysis revealed that SOT-COM was a significant independent factor associated with OH. The area under the curve (AUC) of SOT-COM was 0.833 (95% confidence interval: 0.778–0.887, p < 0.001), with a sensitivity of 0.826 and a specificity of 0.759. Conclusions: This study demonstrates that older individuals with OH are more prone to falls, due to decreased sensory integration for balance. |
format | Online Article Text |
id | pubmed-10606146 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106061462023-10-28 Quantitative Assessment of Balance Function Characteristics in Older Patients with Orthostatic Hypotension Cui, Yao Liu, Bo Zhou, Jian Liu, Qian Ye, Hui Geriatrics (Basel) Article Background: Orthostatic hypotension (OH) is a common blood pressure abnormality in older adults that makes them prone to balance disorders and falls. The maintenance of balance relies on a complex regulatory system. The use of computerized dynamic posturography (CDP) can provide a quantitative evaluation of balance function. The objective of this study was to utilize CDP to measure balance indicators in older individuals with OH. Methods: A total of 303 older adults were divided into an OH group of 91 and a non-OH group of 212. Various factors, including chronic diseases, medication history, laboratory tests, and balance indicators, were compared between the two groups. Results: ① Participants with OH had more chronic diseases, including coronary heart disease (p = 0.049) and a history of falls (p < 0.001), than those without OH. A history of multiple medications in the OH group was significantly more likely than in the non-OH group (p = 0.006). ② There was a significant reduction in the composite equilibrium score (SOT-COM) (p < 0.001), vision ratio score (VIS) (p < 0.001), vestibular ratio score (VEST) (p < 0.001), and directional control (DCL) (p = 0.028) in the OH group. ③ A logistic regression analysis revealed that SOT-COM was a significant independent factor associated with OH. The area under the curve (AUC) of SOT-COM was 0.833 (95% confidence interval: 0.778–0.887, p < 0.001), with a sensitivity of 0.826 and a specificity of 0.759. Conclusions: This study demonstrates that older individuals with OH are more prone to falls, due to decreased sensory integration for balance. MDPI 2023-10-18 /pmc/articles/PMC10606146/ /pubmed/37887976 http://dx.doi.org/10.3390/geriatrics8050103 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cui, Yao Liu, Bo Zhou, Jian Liu, Qian Ye, Hui Quantitative Assessment of Balance Function Characteristics in Older Patients with Orthostatic Hypotension |
title | Quantitative Assessment of Balance Function Characteristics in Older Patients with Orthostatic Hypotension |
title_full | Quantitative Assessment of Balance Function Characteristics in Older Patients with Orthostatic Hypotension |
title_fullStr | Quantitative Assessment of Balance Function Characteristics in Older Patients with Orthostatic Hypotension |
title_full_unstemmed | Quantitative Assessment of Balance Function Characteristics in Older Patients with Orthostatic Hypotension |
title_short | Quantitative Assessment of Balance Function Characteristics in Older Patients with Orthostatic Hypotension |
title_sort | quantitative assessment of balance function characteristics in older patients with orthostatic hypotension |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606146/ https://www.ncbi.nlm.nih.gov/pubmed/37887976 http://dx.doi.org/10.3390/geriatrics8050103 |
work_keys_str_mv | AT cuiyao quantitativeassessmentofbalancefunctioncharacteristicsinolderpatientswithorthostatichypotension AT liubo quantitativeassessmentofbalancefunctioncharacteristicsinolderpatientswithorthostatichypotension AT zhoujian quantitativeassessmentofbalancefunctioncharacteristicsinolderpatientswithorthostatichypotension AT liuqian quantitativeassessmentofbalancefunctioncharacteristicsinolderpatientswithorthostatichypotension AT yehui quantitativeassessmentofbalancefunctioncharacteristicsinolderpatientswithorthostatichypotension |