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The Clinical and Molecular Profile of Lung Cancer Patients Harboring the TP53 R337H Germline Variant in a Brazilian Cancer Center: The Possible Mechanism of Carcinogenesis
In southern and southeastern Brazil, the TP53 founder variant c.1010G>A (R337H) has been previously documented with a prevalence of 0.3% within the general population and linked to a heightened incidence of lung adenocarcinomas (LUADs). In the present investigation, we cover clinical and molecula...
Autores principales: | Lopes, Carlos D. H., Antonacio, Fernanda F., Moraes, Priscila M. G., Asprino, Paula F., Galante, Pedro A. F., Jardim, Denis L., de Macedo, Mariana P., Sandoval, Renata L., Katz, Artur, de Castro, Gilberto, Achatz, Maria Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606350/ https://www.ncbi.nlm.nih.gov/pubmed/37894716 http://dx.doi.org/10.3390/ijms242015035 |
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