Cargando…
Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China
Han is the largest of China’s 56 ethnic groups and the most populous ethnic group in the world. The Luzhou region is located in southwest China, at the junction of three provinces. The unique historical factors contribute to the genetic polymorphism information. Short tandem repeats (STRs) are highl...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606688/ https://www.ncbi.nlm.nih.gov/pubmed/37895253 http://dx.doi.org/10.3390/genes14101904 |
_version_ | 1785127375708618752 |
---|---|
author | Fu, Jiewen Song, Binghui Qian, Jie He, Ting Chen, Hanchun Cheng, Jingliang Fu, Junjiang |
author_facet | Fu, Jiewen Song, Binghui Qian, Jie He, Ting Chen, Hanchun Cheng, Jingliang Fu, Junjiang |
author_sort | Fu, Jiewen |
collection | PubMed |
description | Han is the largest of China’s 56 ethnic groups and the most populous ethnic group in the world. The Luzhou region is located in southwest China, at the junction of three provinces. The unique historical factors contribute to the genetic polymorphism information. Short tandem repeats (STRs) are highly polymorphic, but the polymorphism of the Y chromosomal STRs (Y-STRs) loci in the Luzhou region is still unclear. It is of great significance to provide Y-STRs genetic data for the Han population from the Luzhou areas of southwest China. A total of 910 unrelated male individuals of the Han population from the Luzhou area were recruited, and 24 Y-STRs were analyzed. The population structure and phylogenetic relationships were compared with those of another 11 related Han populations. A total of 893 different haplotypes were achieved from 910 samples, of which 877 (98.21%) haplotypes were unique. Haplotype diversity and discrimination were 0.999956 and 0.981319, respectively. The lowest genetic diversity of DYS437 is 0.4321, and the highest genetic diversity of DYS385a/b is 0.9642. Pair-to-pair genetic distance and relative probability values indicate that Luzhou Han people are close to Sichuan Han people, Guangdong Han people, and Hunan Han people, which is consistent with geographical distribution, historical influence, and economic development. The 24 Y-STR markers of the southwest Luzhou Han population were highly polymorphic, which provided us with genetic polymorphism information and enriched the population genetic database. Therefore, it is of great value to our forensic applications and population genetics research. |
format | Online Article Text |
id | pubmed-10606688 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106066882023-10-28 Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China Fu, Jiewen Song, Binghui Qian, Jie He, Ting Chen, Hanchun Cheng, Jingliang Fu, Junjiang Genes (Basel) Article Han is the largest of China’s 56 ethnic groups and the most populous ethnic group in the world. The Luzhou region is located in southwest China, at the junction of three provinces. The unique historical factors contribute to the genetic polymorphism information. Short tandem repeats (STRs) are highly polymorphic, but the polymorphism of the Y chromosomal STRs (Y-STRs) loci in the Luzhou region is still unclear. It is of great significance to provide Y-STRs genetic data for the Han population from the Luzhou areas of southwest China. A total of 910 unrelated male individuals of the Han population from the Luzhou area were recruited, and 24 Y-STRs were analyzed. The population structure and phylogenetic relationships were compared with those of another 11 related Han populations. A total of 893 different haplotypes were achieved from 910 samples, of which 877 (98.21%) haplotypes were unique. Haplotype diversity and discrimination were 0.999956 and 0.981319, respectively. The lowest genetic diversity of DYS437 is 0.4321, and the highest genetic diversity of DYS385a/b is 0.9642. Pair-to-pair genetic distance and relative probability values indicate that Luzhou Han people are close to Sichuan Han people, Guangdong Han people, and Hunan Han people, which is consistent with geographical distribution, historical influence, and economic development. The 24 Y-STR markers of the southwest Luzhou Han population were highly polymorphic, which provided us with genetic polymorphism information and enriched the population genetic database. Therefore, it is of great value to our forensic applications and population genetics research. MDPI 2023-10-02 /pmc/articles/PMC10606688/ /pubmed/37895253 http://dx.doi.org/10.3390/genes14101904 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Fu, Jiewen Song, Binghui Qian, Jie He, Ting Chen, Hanchun Cheng, Jingliang Fu, Junjiang Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China |
title | Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China |
title_full | Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China |
title_fullStr | Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China |
title_full_unstemmed | Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China |
title_short | Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China |
title_sort | genetic polymorphism analysis of 24 y-strs in a han chinese population in luzhou, southwest china |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606688/ https://www.ncbi.nlm.nih.gov/pubmed/37895253 http://dx.doi.org/10.3390/genes14101904 |
work_keys_str_mv | AT fujiewen geneticpolymorphismanalysisof24ystrsinahanchinesepopulationinluzhousouthwestchina AT songbinghui geneticpolymorphismanalysisof24ystrsinahanchinesepopulationinluzhousouthwestchina AT qianjie geneticpolymorphismanalysisof24ystrsinahanchinesepopulationinluzhousouthwestchina AT heting geneticpolymorphismanalysisof24ystrsinahanchinesepopulationinluzhousouthwestchina AT chenhanchun geneticpolymorphismanalysisof24ystrsinahanchinesepopulationinluzhousouthwestchina AT chengjingliang geneticpolymorphismanalysisof24ystrsinahanchinesepopulationinluzhousouthwestchina AT fujunjiang geneticpolymorphismanalysisof24ystrsinahanchinesepopulationinluzhousouthwestchina |