Study of the Structural Chemistry of the Inclusion Complexation of 4-Phenylbutyrate and Related Compounds with Cyclodextrins in Solution: Differences in Inclusion Mode with Cavity Size Dependency

4-phenylbutyrate (PB) and structurally related compounds hold promise for treating many diseases, including cancers. However, pharmaceutical limitations, such as an unpleasant taste or poor aqueous solubility, impede their evaluation and clinical use. This study explores cyclodextrin (CD) complexati...

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Detalles Bibliográficos
Autores principales: Commey, Kindness L., Nakatake, Akari, Enaka, Airi, Nakamura, Ryota, Nishi, Koji, Tsukigawa, Kenji, Ikeda, Hirohito, Yamaguchi, Koki, Iohara, Daisuke, Hirayama, Fumitoshi, Yamasaki, Keishi, Otagiri, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606765/
https://www.ncbi.nlm.nih.gov/pubmed/37894771
http://dx.doi.org/10.3390/ijms242015091

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