A Methodological Approach to Identify Natural Compounds with Antifibrotic Activity and the Potential to Treat Pulmonary Fibrosis Using Single-Cell Sequencing and Primary Human Lung Macrophages

Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of the interstitial pneumonias. The cause of the disease is unknown, and new therapies that stop or reverse disease progression are desperately needed. Recent advances in next-generation sequencing have led to an abundance of fre...

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Detalles Bibliográficos
Autores principales: Apte, Simon H., Groves, Penny L., Tan, Maxine E., Lutzky, Viviana P., de Silva, Tharushi, Monteith, Joshua N., Yerkovich, Stephanie T., O’Sullivan, Brendan J., Davis, Rohan A., Chambers, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606775/
https://www.ncbi.nlm.nih.gov/pubmed/37894784
http://dx.doi.org/10.3390/ijms242015104

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