Bioengineered Hybrid Rep 2/6 Gene Improves Encapsulation of a Single-Stranded Expression Cassette into AAV6 Vectors

The production of clinical-grade recombinant adeno-associated viral (AAV) vectors for gene therapy trials remains a major hurdle in the further advancement of the gene therapy field. During the past decades, AAV research has been predominantly focused on the development of new capsid modifications,...

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Detalles Bibliográficos
Autores principales: Tejero, Marcos, Duzenli, Ozgun F., Caine, Colin, Kuoch, Hisae, Aslanidi, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606878/
https://www.ncbi.nlm.nih.gov/pubmed/37895215
http://dx.doi.org/10.3390/genes14101866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10606878/
https://www.ncbi.nlm.nih.gov/pubmed/37895215
http://dx.doi.org/10.3390/genes14101866

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