Multi-Omics of Familial Thoracic Aortic Aneurysm and Dissection: Calcium Transport Impairment Predisposes Aortas to Dissection

Several genetic defects, including a mutation in myosin heavy chain 11 (Myh11), are reported to cause familial thoracic aortic aneurysm and dissection (FTAAD). We recently showed that mice lacking K1256 of Myh11 developed aortic dissection when stimulated with angiotensin II, despite the absence of...

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Detalles Bibliográficos
Autores principales: Tomida, Shota, Ishima, Tamaki, Sawaki, Daigo, Imai, Yasushi, Nagai, Ryozo, Aizawa, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607035/
https://www.ncbi.nlm.nih.gov/pubmed/37894894
http://dx.doi.org/10.3390/ijms242015213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607035/
https://www.ncbi.nlm.nih.gov/pubmed/37894894
http://dx.doi.org/10.3390/ijms242015213

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