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Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches

Within the human body, the intricate network of blood vessels plays a pivotal role in transporting nutrients and oxygen and maintaining homeostasis. Bioprinting is an innovative technology with the potential to revolutionize this field by constructing complex multicellular structures. This technique...

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Autores principales: Choi, Jaewoo, Lee, Eun Ji, Jang, Woong Bi, Kwon, Sang-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607080/
https://www.ncbi.nlm.nih.gov/pubmed/37888162
http://dx.doi.org/10.3390/jfb14100497
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author Choi, Jaewoo
Lee, Eun Ji
Jang, Woong Bi
Kwon, Sang-Mo
author_facet Choi, Jaewoo
Lee, Eun Ji
Jang, Woong Bi
Kwon, Sang-Mo
author_sort Choi, Jaewoo
collection PubMed
description Within the human body, the intricate network of blood vessels plays a pivotal role in transporting nutrients and oxygen and maintaining homeostasis. Bioprinting is an innovative technology with the potential to revolutionize this field by constructing complex multicellular structures. This technique offers the advantage of depositing individual cells, growth factors, and biochemical signals, thereby facilitating the growth of functional blood vessels. Despite the challenges in fabricating vascularized constructs, bioprinting has emerged as an advance in organ engineering. The continuous evolution of bioprinting technology and biomaterial knowledge provides an avenue to overcome the hurdles associated with vascularized tissue fabrication. This article provides an overview of the biofabrication process used to create vascular and vascularized constructs. It delves into the various techniques used in vascular engineering, including extrusion-, droplet-, and laser-based bioprinting methods. Integrating these techniques offers the prospect of crafting artificial blood vessels with remarkable precision and functionality. Therefore, the potential impact of bioprinting in vascular engineering is significant. With technological advances, it holds promise in revolutionizing organ transplantation, tissue engineering, and regenerative medicine. By mimicking the natural complexity of blood vessels, bioprinting brings us one step closer to engineering organs with functional vasculature, ushering in a new era of medical advancement.
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spelling pubmed-106070802023-10-28 Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches Choi, Jaewoo Lee, Eun Ji Jang, Woong Bi Kwon, Sang-Mo J Funct Biomater Review Within the human body, the intricate network of blood vessels plays a pivotal role in transporting nutrients and oxygen and maintaining homeostasis. Bioprinting is an innovative technology with the potential to revolutionize this field by constructing complex multicellular structures. This technique offers the advantage of depositing individual cells, growth factors, and biochemical signals, thereby facilitating the growth of functional blood vessels. Despite the challenges in fabricating vascularized constructs, bioprinting has emerged as an advance in organ engineering. The continuous evolution of bioprinting technology and biomaterial knowledge provides an avenue to overcome the hurdles associated with vascularized tissue fabrication. This article provides an overview of the biofabrication process used to create vascular and vascularized constructs. It delves into the various techniques used in vascular engineering, including extrusion-, droplet-, and laser-based bioprinting methods. Integrating these techniques offers the prospect of crafting artificial blood vessels with remarkable precision and functionality. Therefore, the potential impact of bioprinting in vascular engineering is significant. With technological advances, it holds promise in revolutionizing organ transplantation, tissue engineering, and regenerative medicine. By mimicking the natural complexity of blood vessels, bioprinting brings us one step closer to engineering organs with functional vasculature, ushering in a new era of medical advancement. MDPI 2023-10-08 /pmc/articles/PMC10607080/ /pubmed/37888162 http://dx.doi.org/10.3390/jfb14100497 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Choi, Jaewoo
Lee, Eun Ji
Jang, Woong Bi
Kwon, Sang-Mo
Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches
title Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches
title_full Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches
title_fullStr Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches
title_full_unstemmed Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches
title_short Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches
title_sort development of biocompatible 3d-printed artificial blood vessels through multidimensional approaches
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607080/
https://www.ncbi.nlm.nih.gov/pubmed/37888162
http://dx.doi.org/10.3390/jfb14100497
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