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Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip
The Mg alloy vascular clip has biodegradability and good biocompatibility, which can improve the convenience and safety of clinical application. However, the Mg alloy vascular clip also has some disadvantages, such as an unreasonable structure design and a degradation rate which is too fast. In this...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607122/ https://www.ncbi.nlm.nih.gov/pubmed/37888166 http://dx.doi.org/10.3390/jfb14100501 |
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author | Zhang, Hongxu Gao, Ming Tian, Xiaoying Cao, Dali Tan, Lili |
author_facet | Zhang, Hongxu Gao, Ming Tian, Xiaoying Cao, Dali Tan, Lili |
author_sort | Zhang, Hongxu |
collection | PubMed |
description | The Mg alloy vascular clip has biodegradability and good biocompatibility, which can improve the convenience and safety of clinical application. However, the Mg alloy vascular clip also has some disadvantages, such as an unreasonable structure design and a degradation rate which is too fast. In this study, the process of clamping blood vessels with a biodegradable Mg alloy (Mg-Zn-Nd-Zr and Mg-Zn-Nd) general V-type vascular clip was simulated by finite element simulation software (Abaqus). A new type of vascular clip, the P-type vascular clip, was analyzed and investigated through simulation. The differences between Mg alloy vascular clips of V-type and P-type were analyzed by finite element simulation. In addition, the effects of Zr element on the mechanical properties and corrosion resistance of P-type vascular clips were also investigated to improve the mechanical stability. The results show that during the V-type vascular clip closure of Mg-Zn-Nd-Zr alloy, this clip has some problems, such as uneven distribution of blood vessel stress, crevices in blood vessels and stress concentration. The improved P-type vascular clip has uniform closure, and there is no gap in the blood vessel, which can effectively avoid stress concentration. The improved P-type vascular clip is well closed and can effectively avoid stress concentration. The corrosion resistance of the Mg-Zn-Nd-Zr alloy P-type clip was better than that of the Mg-Zn-Nd alloy P-type clip (degradation rate of 2.02 mm/y and 2.61 mm/y on the 7th day, respectively). Mg-Zn-Nd-Zr alloy The P-type vascular clip remained closed even on the 7th day, which could meet the requirements of clinical application. |
format | Online Article Text |
id | pubmed-10607122 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106071222023-10-28 Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip Zhang, Hongxu Gao, Ming Tian, Xiaoying Cao, Dali Tan, Lili J Funct Biomater Article The Mg alloy vascular clip has biodegradability and good biocompatibility, which can improve the convenience and safety of clinical application. However, the Mg alloy vascular clip also has some disadvantages, such as an unreasonable structure design and a degradation rate which is too fast. In this study, the process of clamping blood vessels with a biodegradable Mg alloy (Mg-Zn-Nd-Zr and Mg-Zn-Nd) general V-type vascular clip was simulated by finite element simulation software (Abaqus). A new type of vascular clip, the P-type vascular clip, was analyzed and investigated through simulation. The differences between Mg alloy vascular clips of V-type and P-type were analyzed by finite element simulation. In addition, the effects of Zr element on the mechanical properties and corrosion resistance of P-type vascular clips were also investigated to improve the mechanical stability. The results show that during the V-type vascular clip closure of Mg-Zn-Nd-Zr alloy, this clip has some problems, such as uneven distribution of blood vessel stress, crevices in blood vessels and stress concentration. The improved P-type vascular clip has uniform closure, and there is no gap in the blood vessel, which can effectively avoid stress concentration. The improved P-type vascular clip is well closed and can effectively avoid stress concentration. The corrosion resistance of the Mg-Zn-Nd-Zr alloy P-type clip was better than that of the Mg-Zn-Nd alloy P-type clip (degradation rate of 2.02 mm/y and 2.61 mm/y on the 7th day, respectively). Mg-Zn-Nd-Zr alloy The P-type vascular clip remained closed even on the 7th day, which could meet the requirements of clinical application. MDPI 2023-10-09 /pmc/articles/PMC10607122/ /pubmed/37888166 http://dx.doi.org/10.3390/jfb14100501 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhang, Hongxu Gao, Ming Tian, Xiaoying Cao, Dali Tan, Lili Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
title | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
title_full | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
title_fullStr | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
title_full_unstemmed | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
title_short | Study on Mechanical Properties and Degradation Behavior of Magnesium Alloy Vascular Clip |
title_sort | study on mechanical properties and degradation behavior of magnesium alloy vascular clip |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607122/ https://www.ncbi.nlm.nih.gov/pubmed/37888166 http://dx.doi.org/10.3390/jfb14100501 |
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