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Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age

This longitudinal study aimed to evaluate facial growth and soft tissue changes in infants with complete unilateral cleft lip, alveolus, and palate (CUCLAP) at ages 3, 9, and 12 months. Using 3D images of 22 CUCLAP infants, average faces and distance maps for the entire face and specific regions wer...

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Autores principales: Kluge, Jennifer, Bruggink, Robin, Pandis, Nikolaos, Unkovskiy, Alexey, Jost-Brinkmann, Paul-Georg, Kuijpers-Jagtman, Anne Marie, Bartzela, Theodosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607132/
https://www.ncbi.nlm.nih.gov/pubmed/37892569
http://dx.doi.org/10.3390/jcm12206432
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author Kluge, Jennifer
Bruggink, Robin
Pandis, Nikolaos
Unkovskiy, Alexey
Jost-Brinkmann, Paul-Georg
Kuijpers-Jagtman, Anne Marie
Bartzela, Theodosia
author_facet Kluge, Jennifer
Bruggink, Robin
Pandis, Nikolaos
Unkovskiy, Alexey
Jost-Brinkmann, Paul-Georg
Kuijpers-Jagtman, Anne Marie
Bartzela, Theodosia
author_sort Kluge, Jennifer
collection PubMed
description This longitudinal study aimed to evaluate facial growth and soft tissue changes in infants with complete unilateral cleft lip, alveolus, and palate (CUCLAP) at ages 3, 9, and 12 months. Using 3D images of 22 CUCLAP infants, average faces and distance maps for the entire face and specific regions were created. Color-coded maps highlighted more significant soft tissue changes from 3 to 9 months than from 9 to 12 months. The first interval showed substantial growth in the entire face, particularly in the forehead, eyes, lower lip, chin, and cheeks (p < 0.001), while the second interval exhibited no significant growth. This study provides insights into facial soft tissue growth in CUCLAP infants during critical developmental stages, emphasizing substantial improvements between 3 and 9 months, mainly in the chin, lower lip, and forehead. However, uneven growth occurred in the upper lip, philtrum, and nostrils throughout both intervals, with an overall decline in growth from 9 to 12 months. These findings underscore the dynamic nature of soft tissue growth in CUCLAP patients, highlighting the need to consider these patterns in treatment planning. Future research should explore the underlying factors and develop customized treatment interventions for enhanced facial aesthetics and function in this population.
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spelling pubmed-106071322023-10-28 Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age Kluge, Jennifer Bruggink, Robin Pandis, Nikolaos Unkovskiy, Alexey Jost-Brinkmann, Paul-Georg Kuijpers-Jagtman, Anne Marie Bartzela, Theodosia J Clin Med Article This longitudinal study aimed to evaluate facial growth and soft tissue changes in infants with complete unilateral cleft lip, alveolus, and palate (CUCLAP) at ages 3, 9, and 12 months. Using 3D images of 22 CUCLAP infants, average faces and distance maps for the entire face and specific regions were created. Color-coded maps highlighted more significant soft tissue changes from 3 to 9 months than from 9 to 12 months. The first interval showed substantial growth in the entire face, particularly in the forehead, eyes, lower lip, chin, and cheeks (p < 0.001), while the second interval exhibited no significant growth. This study provides insights into facial soft tissue growth in CUCLAP infants during critical developmental stages, emphasizing substantial improvements between 3 and 9 months, mainly in the chin, lower lip, and forehead. However, uneven growth occurred in the upper lip, philtrum, and nostrils throughout both intervals, with an overall decline in growth from 9 to 12 months. These findings underscore the dynamic nature of soft tissue growth in CUCLAP patients, highlighting the need to consider these patterns in treatment planning. Future research should explore the underlying factors and develop customized treatment interventions for enhanced facial aesthetics and function in this population. MDPI 2023-10-10 /pmc/articles/PMC10607132/ /pubmed/37892569 http://dx.doi.org/10.3390/jcm12206432 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kluge, Jennifer
Bruggink, Robin
Pandis, Nikolaos
Unkovskiy, Alexey
Jost-Brinkmann, Paul-Georg
Kuijpers-Jagtman, Anne Marie
Bartzela, Theodosia
Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age
title Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age
title_full Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age
title_fullStr Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age
title_full_unstemmed Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age
title_short Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age
title_sort longitudinal three-dimensional stereophotogrammetric growth analysis in infants with unilateral cleft lip and palate from 3 to 12 months of age
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607132/
https://www.ncbi.nlm.nih.gov/pubmed/37892569
http://dx.doi.org/10.3390/jcm12206432
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