Loss of Sec-1 Family Domain-Containing 1 (scfd1) Causes Severe Cardiac Defects and Endoplasmic Reticulum Stress in Zebrafish

Dilated cardiomyopathy (DCM) is a common heart muscle disorder that frequently leads to heart failure, arrhythmias, and death. While DCM is often heritable, disease-causing mutations are identified in only ~30% of cases. In a forward genetic mutagenesis screen, we identified a novel zebrafish mutant...

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Detalles Bibliográficos
Autores principales: Huttner, Inken G., Santiago, Celine F., Jacoby, Arie, Cheng, Delfine, Trivedi, Gunjan, Cull, Stephen, Cvetkovska, Jasmina, Chand, Renee, Berger, Joachim, Currie, Peter D., Smith, Kelly A., Fatkin, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607167/
https://www.ncbi.nlm.nih.gov/pubmed/37887855
http://dx.doi.org/10.3390/jcdd10100408

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