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Ceramide Is Involved in Temozolomide Resistance in Human Glioblastoma U87MG Overexpressing EGFR

Glioblastoma multiforme (GBM) is the most frequent and deadly brain tumor. Many sphingolipids are crucial players in the regulation of glioma cell growth as well as in the response to different chemotherapeutic drugs. In particular, ceramide (Cer) is a tumor suppressor lipid, able to induce antiprol...

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Detalles Bibliográficos
Autores principales: Bassi, Rosaria, Dei Cas, Michele, Tringali, Cristina, Compostella, Federica, Paroni, Rita, Giussani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607229/
https://www.ncbi.nlm.nih.gov/pubmed/37895074
http://dx.doi.org/10.3390/ijms242015394