Local Net Charge State of Collagen Triple Helix Is a Determinant of FKBP22 Binding to Collagen III

Mutations in the FKBP14 gene encoding the endoplasmic reticulum resident collagen-related proline isomerase FK506 binding protein 22 kDa (FKBP22) result in kyphoscoliotic Ehlers–Danlos Syndrome (EDS), which is characterized by a broad phenotypic outcome. A plausible explanation for this outcome is t...

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Detalles Bibliográficos
Autores principales: Ishikawa, Yoshihiro, Bonna, Arkadiusz, Gould, Douglas B., Farndale, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607241/
https://www.ncbi.nlm.nih.gov/pubmed/37894834
http://dx.doi.org/10.3390/ijms242015156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607241/
https://www.ncbi.nlm.nih.gov/pubmed/37894834
http://dx.doi.org/10.3390/ijms242015156

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