Cargando…

Network Pharmacology and Bioinformatics Study of Geniposide Regulating Oxidative Stress in Colorectal Cancer

This study aims to identify the mechanism of geniposide regulating oxidative stress in colorectal cancer (CRC) through network pharmacology and bioinformatics analysis. Targets of geniposide, oxidative stress-related targets and targets related to CRC were applied from databases. The hub genes for g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yingzi, Luo, Jinhai, Xu, Baojun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607277/ https://www.ncbi.nlm.nih.gov/pubmed/37894904 http://dx.doi.org/10.3390/ijms242015222

Ejemplares similares

Network pharmacology and bioinformatics to identify the molecular mechanisms of Gleditsiae Spina against colorectal cancer
por: Wu, Yingzi, et al.
Publicado: (2023)

Diverse Pharmacological Activities and Potential Medicinal Benefits of Geniposide
por: Zhou, Yan-Xi, et al.
Publicado: (2019)

Updated Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of Natural Product Geniposide
por: Liu, Liping, et al.
Publicado: (2022)

A Review on the Phytochemistry, Pharmacology, Pharmacokinetics and Toxicology of Geniposide, a Natural Product
por: Shan, Mingqiu, et al.
Publicado: (2017)

Protective effect and possible mechanisms of geniposide for ischemia-reperfusion injury: A systematic review with meta-analysis and network pharmacology of preclinical evidence
por: Luo, Chaoqin, et al.
Publicado: (2023)

Studies Based on Preparation, Physical Characteristics, and Cellular Pharmacological Activities of Thin PLGA Film Loaded with Geniposide
por: Zhang, Haiyan, et al.
Publicado: (2014)

Effects of Fructus Psoraleae Extract on the Intestinal Absorption Kinetics of Geniposide and Geniposidic Acid in Rat
por: Huo, Yan, et al.
Publicado: (2014)

Geniposide attenuates cadmium-induced oxidative stress injury via Nrf2 signaling in osteoblasts
por: He, Tengfeng, et al.
Publicado: (2019)

Plant-Derived Anticancer Agents: Lessons from the Pharmacology of Geniposide and Its Aglycone, Genipin
por: Habtemariam, Solomon, et al.
Publicado: (2018)

Geniposide Alleviates Oxidative Stress of Mice With Depression-Like Behaviors by Upregulating Six3os1
por: Zou, Tianyu, et al.
Publicado: (2020)

Geniposide Causes Idiopathic Mesenteric Phlebosclerosis
por: Young Chuah, Yoen, et al.
Publicado: (2023)

In Vitro Selection of DNA Aptamers that Binds Geniposide
por: Zhang, Aozhe, et al.
Publicado: (2017)

Mechanistic insights into geniposide regulation of bile salt export pump (BSEP) expression
por: Wu, Guixin, et al.
Publicado: (2018)

Combined Administration of Vitamin D(3) and Geniposide Is Less Effective than Single Use of Vitamin D(3) or Geniposide in the Treatment of Ulcerative Colitis
por: Lu, Yingyu, et al.
Publicado: (2021)

Geniposide Improves Diabetic Nephropathy by Enhancing ULK1-Mediated Autophagy and Reducing Oxidative Stress through AMPK Activation
por: Dusabimana, Theodomir, et al.
Publicado: (2021)

Geniposide Ameliorates Liver Fibrosis Through Reducing Oxidative Stress and Inflammatory Respose, Inhibiting Apoptosis and Modulating Overall Metabolism
por: Yang, Lu, et al.
Publicado: (2021)

Geniposide Attenuates Hyperglycemia-Induced Oxidative Stress and Inflammation by Activating the Nrf2 Signaling Pathway in Experimental Diabetic Retinopathy
por: Tu, Yuanyuan, et al.
Publicado: (2021)

Integrated bioinformatics, network pharmacology, and artificial intelligence to predict the mechanism of celastrol against muscle atrophy caused by colorectal cancer
por: Wu, Ming, et al.
Publicado: (2022)

Geniposide Possesses the Protective Effect on Myocardial Injury by Inhibiting Oxidative Stress and Ferroptosis via Activation of the Grsf1/GPx4 Axis
por: Shen, Yuehong, et al.
Publicado: (2022)

Lactobacillus casei Strain Shirota Enhances the Ability of Geniposide to Activate SIRT1 and Decrease Inflammation and Oxidative Stress in Septic Mice
por: Mai, Chao, et al.
Publicado: (2021)

Integrated bioinformatics analysis of expression and gene regulation network of COL12A1 in colorectal cancer
por: Wu, Yibin, et al.
Publicado: (2020)

Eucommia ulmoides Oliver Extract, Aucubin, and Geniposide Enhance Lysosomal Activity to Regulate ER Stress and Hepatic Lipid Accumulation
por: Lee, Hwa-Young, et al.
Publicado: (2013)

Integrated network pharmacology, bioinformatics, and molecular docking to explore the mechanisms of berberine regulating autophagy in breast cancer
por: Huang, Bowan, et al.
Publicado: (2023)

The emerging possibility of the use of geniposide in the treatment of cerebral diseases: a review
por: Zhang, Wenwen, et al.
Publicado: (2021)

Metabolomics and Proteomics Annotate Therapeutic Properties of Geniposide: Targeting and Regulating Multiple Perturbed Pathways
por: Wang, Xijun, et al.
Publicado: (2013)

Eucommia ulmoides Cortex, Geniposide and Aucubin Regulate Lipotoxicity through the Inhibition of Lysosomal BAX
por: Lee, Geum-Hwa, et al.
Publicado: (2014)

Selective Extraction of Gardenia Yellow and Geniposide from Gardenia jasminoides by Mechanochemistry
por: Xu, Wenhao, et al.
Publicado: (2016)

Protective properties of geniposide against UV-B-induced photooxidative stress in human dermal fibroblasts
por: Shin, Daehyun, et al.
Publicado: (2018)

The mechanism of dehydroandrographolide inhibiting metastasis in gastric cancer based on network pharmacology and bioinformatics
por: Luo, Yan-hai, et al.
Publicado: (2023)

Geniposidic Acid from Eucommia ulmoides Oliver Staminate Flower Tea Mitigates Cellular Oxidative Stress via Activating AKT/NRF2 Signaling
por: Cheng, Shuo, et al.
Publicado: (2022)

The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde
por: Sun, Ping, et al.
Publicado: (2013)

Geniposide prevents rotenone-induced apoptosis in primary cultured neurons
por: Li, Lin, et al.
Publicado: (2015)

The Beneficial Effects of Geniposide on Glucose and Lipid Metabolism: A Review
por: Gao, Siting, et al.
Publicado: (2022)

Biotransformation of Geniposide into Genipin by Immobilized Trichoderma reesei and Conformational Study of Genipin
por: Yang, Yishun, et al.
Publicado: (2018)

A New Geniposidic Acid Derivative Exerts Antiaging Effects through Antioxidative Stress and Autophagy Induction
por: Wang, Ying, et al.
Publicado: (2021)

Pharmacological Regulation of Oxidative Stress in Stem Cells
por: Lee, Jungwoon, et al.
Publicado: (2018)

A mucoadhesive, thermoreversible in situ nasal gel of geniposide for neurodegenerative diseases
por: Wang, Yingting, et al.
Publicado: (2017)

Idiopathic mesenteric phlebosclerosis associated with long-term oral intake of geniposide
por: Wen, Yang, et al.
Publicado: (2021)

Anti-inflammatory action of geniposide promotes wound healing in diabetic rats
por: Chen, Xiao-yan, et al.
Publicado: (2022)

Peptide modified geniposidic acid targets bone and effectively promotes osteogenesis
por: Liu, Meijing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_im1d3jpntb5fgd16a32nkog93t