The PKG Inhibitor CN238 Affords Functional Protection of Photoreceptors and Ganglion Cells against Retinal Degeneration

Hereditary retinal degeneration (RD) is often associated with excessive cGMP signalling in photoreceptors. Previous research has shown that inhibition of cGMP-dependent protein kinase G (PKG) can reduce photoreceptor loss in two different RD animal models. In this study, we identified a PKG inhibito...

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Detalles Bibliográficos
Autores principales: Tolone, Arianna, Haq, Wadood, Fachinger, Alexandra, Roy, Akanksha, Kesh, Sandeep, Rentsch, Andreas, Wucherpfennig, Sophie, Zhu, Yu, Groten, John, Schwede, Frank, Tomar, Tushar, Herberg, Friedrich W., Nache, Vasilica, Paquet-Durand, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607377/
https://www.ncbi.nlm.nih.gov/pubmed/37894958
http://dx.doi.org/10.3390/ijms242015277

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