Cargando…

Evaluation of Density-Based Spatial Clustering for Identifying Genomic Loci Associated with Ischemic Stroke in Genome-Wide Data

The genetic architecture of ischemic stroke (IS), which is one of the leading causes of death worldwide, is complex and underexplored. The traditional approach for associative gene mapping is genome-wide association studies (GWASs), testing individual single-nucleotide polymorphisms (SNPs) across th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khvorykh, Gennady V., Sapozhnikov, Nikita A., Limborska, Svetlana A., Khrunin, Andrey V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607504/ https://www.ncbi.nlm.nih.gov/pubmed/37895035 http://dx.doi.org/10.3390/ijms242015355

Ejemplares similares

A Workflow for Selection of Single Nucleotide Polymorphic Markers for Studying of Genetics of Ischemic Stroke Outcomes
por: Khvorykh, Gennady, et al.
Publicado: (2021)

Genomic landscape of the signals of positive natural selection in populations of Northern Eurasia: A view from Northern Russia
por: Khrunin, Andrey V., et al.
Publicado: (2020)

Examination of Genetic Variants Revealed from a Rat Model of Brain Ischemia in Patients with Ischemic Stroke: A Pilot Study
por: Khrunin, Andrey V., et al.
Publicado: (2021)

Analysis of Common SNPs across Continents Reveals Major Genomic Differences between Human Populations
por: Fedorova, Larisa, et al.
Publicado: (2022)

The Study of the Association of Polymorphisms in LSP1, GPNMB, PDPN, TAGLN, TSPO, and TUBB6 Genes with the Risk and Outcome of Ischemic Stroke in the Russian Population
por: Khrunin, Andrey V., et al.
Publicado: (2023)

Analysis of DNA variations in GSTA and GSTM gene clusters based on the results of genome-wide data from three Russian populations taken as an example
por: Filippova, Irina N, et al.
Publicado: (2012)

Global Picture of Genetic Relatedness and the Evolution of Humankind
por: Khvorykh, Gennady V., et al.
Publicado: (2020)

Are Ischemic Stroke and Alzheimer’s Disease Genetically Consecutive Pathologies?
por: Filippenkov, Ivan B., et al.
Publicado: (2023)

imputeqc: an R package for assessing imputation quality of genotypes and optimizing imputation parameters
por: Khvorykh, Gennady V., et al.
Publicado: (2020)

GSTM1 copy number variation in the context of single nucleotide polymorphisms in the human GSTM cluster
por: Khrunin, Andrey V., et al.
Publicado: (2016)

Special Issue: “Genomics of Stroke”
por: Limborska, Svetlana A., et al.
Publicado: (2022)

Special Issue “Genomics of Stroke” 2022
por: Limborska, Svetlana A., et al.
Publicado: (2023)

Neuroprotective Peptides and New Strategies for Ischemic Stroke Drug Discoveries
por: Dergunova, Lyudmila V., et al.
Publicado: (2023)

A Genome-Wide Analysis of Populations from European Russia Reveals a New Pole of Genetic Diversity in Northern Europe
por: Khrunin, Andrey V., et al.
Publicado: (2013)

Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci
por: Chen, Hongjie, et al.
Publicado: (2022)

Haplotype frequencies at the DRD2 locus in populations of the East European Plain
por: Flegontova, Olga V, et al.
Publicado: (2009)

Genome‐wide meta‐analysis identifies 3 novel loci associated with stroke
por: Malik, Rainer, et al.
Publicado: (2018)

Isoflurane Anesthesia’s Impact on Gene Expression Patterns of Rat Brains in an Ischemic Stroke Model
por: Shpetko, Yana Y., et al.
Publicado: (2023)

Genome-Wide Association Analysis of Ischemic Stroke in Young Adults
por: Cheng, Yu-Ching, et al.
Publicado: (2011)

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
por: Estrada, Karol, et al.
Publicado: (2012)

Comparative genomics of vertebrate Fox cluster loci
por: Wotton, Karl R, et al.
Publicado: (2006)

The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis
por: Medvedeva, Ekaterina V, et al.
Publicado: (2014)

Genomic Risk Profiling of Ischemic Stroke: Results of an International Genome-Wide Association Meta-Analysis
por: Meschia, James F., et al.
Publicado: (2011)

A high-density genome-wide association with absolute blood monocyte count in domestic sheep identifies novel loci
por: Oliveira, Ryan D., et al.
Publicado: (2022)

Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies
por: Rivadeneira, Fernando, et al.
Publicado: (2009)

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk
por: Lindström, Sara, et al.
Publicado: (2014)

Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan
por: Chen, Shih-Pin, et al.
Publicado: (2022)

Genome-wide association meta-analysis of functional outcome after ischemic stroke
por: Söderholm, Martin, et al.
Publicado: (2019)

Identification of novel biomarkers in ischemic stroke: a genome-wide integrated analysis
por: Xie, Qizhi, et al.
Publicado: (2020)

Genome-wide polygenic risk impact on intracranial aneurysms and acute ischemic stroke
por: Hong, Eun Pyo, et al.
Publicado: (2022)

Detection of susceptibility loci by genome-wide linkage analysis
por: Babron, Marie-Claude, et al.
Publicado: (2005)

Genome-wide scans for loci under selection in humans
por: Ronald, James, et al.
Publicado: (2005)

Genome-wide transcriptome analysis using RNA-Seq reveals a large number of differentially expressed genes in a transient MCAO rat model
por: Dergunova, Lyudmila V., et al.
Publicado: (2018)

Identification of six polymorphisms as novel susceptibility loci for ischemic or hemorrhagic stroke by exome-wide association studies
por: Yamada, Yoshiji, et al.
Publicado: (2017)

Twelve New Genomic Loci Associated With Bone Mineral Density
por: Liu, Lu, et al.
Publicado: (2020)

Nonparametric Bayesian clustering to detect bipolar methylated genomic loci
por: Wu, Xiaowei, et al.
Publicado: (2015)

A genome-wide association study links small-vessel ischemic stroke to autophagy
por: Lee, Tsong-Hai, et al.
Publicado: (2017)

Genome-Wide RNA-Sequencing Reveals Massive Circular RNA Expression Changes of the Neurotransmission Genes in the Rat Brain after Ischemia–Reperfusion
por: Filippenkov, Ivan B., et al.
Publicado: (2021)

Reconstructing genetic history of Siberian and Northeastern European populations
por: Wong, Emily H.M., et al.
Publicado: (2017)

Genome-Wide Association Study Link Novel Loci to Endometriosis
por: Albertsen, Hans M., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ic1ctc4fd08gs8cealafh8as2e