Cargando…

Oral Manifestations of Crohn’s Disease: A Systematic Review

Crohn’s disease (CD) is a chronic inflammatory intestinal condition that can affect the entire gastrointestinal tract. It is characterized by its clinical heterogeneity and irregularities in its course. The etiology and pathogenesis are not well established, so it is difficult to establish an early...

Descripción completa

Detalles Bibliográficos
Autores principales: Pecci-Lloret, María Pilar, Ramirez-Santisteban, Emma, Hergueta-Castillo, Adraz, Guerrero-Gironés, Julia, Oñate-Sánchez, Ricardo Elías
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607549/
https://www.ncbi.nlm.nih.gov/pubmed/37892587
http://dx.doi.org/10.3390/jcm12206450
_version_ 1785127567895822336
author Pecci-Lloret, María Pilar
Ramirez-Santisteban, Emma
Hergueta-Castillo, Adraz
Guerrero-Gironés, Julia
Oñate-Sánchez, Ricardo Elías
author_facet Pecci-Lloret, María Pilar
Ramirez-Santisteban, Emma
Hergueta-Castillo, Adraz
Guerrero-Gironés, Julia
Oñate-Sánchez, Ricardo Elías
author_sort Pecci-Lloret, María Pilar
collection PubMed
description Crohn’s disease (CD) is a chronic inflammatory intestinal condition that can affect the entire gastrointestinal tract. It is characterized by its clinical heterogeneity and irregularities in its course. The etiology and pathogenesis are not well established, so it is difficult to establish an early diagnosis and an effective treatment plan. The objective of this systematic review was to present a qualitative synthesis of the studies referring to the oral manifestations of CD. This systematic review was carried out following the PRISMA guide. Research was conducted in the Pubmed, Web of Science, Scopus, Scielo, and Cocrahne Library databases on 23 February 2023, and updated on 1 September 2023. Articles published between 2012 and 2023 were selected. Articles that analyzed the oral manifestation of CD patients and met the established search terms. In addition, the quality of all the selected studies was analyzed following the CARE guidelines for case reports and the STROBE scale for observational studies. A total of 19 articles were included in this review that met the inclusion criteria. Regarding the oral manifestation of CD, oral ulcers, angular cheilitis, and gingivitis stand out. Periodontitis and vegetative pyostomatitis were the least representative manifestations. The most prevalent locations were lips, mucosa, and gingivae. Ulcers, gingivitis, and angular cheilitis are the most frequent oral manifestations in patients with CD. Their early identification and possible relationship with the disease are important for an early diagnosis and an adequate treatment plan.
format Online
Article
Text
id pubmed-10607549
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-106075492023-10-28 Oral Manifestations of Crohn’s Disease: A Systematic Review Pecci-Lloret, María Pilar Ramirez-Santisteban, Emma Hergueta-Castillo, Adraz Guerrero-Gironés, Julia Oñate-Sánchez, Ricardo Elías J Clin Med Systematic Review Crohn’s disease (CD) is a chronic inflammatory intestinal condition that can affect the entire gastrointestinal tract. It is characterized by its clinical heterogeneity and irregularities in its course. The etiology and pathogenesis are not well established, so it is difficult to establish an early diagnosis and an effective treatment plan. The objective of this systematic review was to present a qualitative synthesis of the studies referring to the oral manifestations of CD. This systematic review was carried out following the PRISMA guide. Research was conducted in the Pubmed, Web of Science, Scopus, Scielo, and Cocrahne Library databases on 23 February 2023, and updated on 1 September 2023. Articles published between 2012 and 2023 were selected. Articles that analyzed the oral manifestation of CD patients and met the established search terms. In addition, the quality of all the selected studies was analyzed following the CARE guidelines for case reports and the STROBE scale for observational studies. A total of 19 articles were included in this review that met the inclusion criteria. Regarding the oral manifestation of CD, oral ulcers, angular cheilitis, and gingivitis stand out. Periodontitis and vegetative pyostomatitis were the least representative manifestations. The most prevalent locations were lips, mucosa, and gingivae. Ulcers, gingivitis, and angular cheilitis are the most frequent oral manifestations in patients with CD. Their early identification and possible relationship with the disease are important for an early diagnosis and an adequate treatment plan. MDPI 2023-10-10 /pmc/articles/PMC10607549/ /pubmed/37892587 http://dx.doi.org/10.3390/jcm12206450 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Pecci-Lloret, María Pilar
Ramirez-Santisteban, Emma
Hergueta-Castillo, Adraz
Guerrero-Gironés, Julia
Oñate-Sánchez, Ricardo Elías
Oral Manifestations of Crohn’s Disease: A Systematic Review
title Oral Manifestations of Crohn’s Disease: A Systematic Review
title_full Oral Manifestations of Crohn’s Disease: A Systematic Review
title_fullStr Oral Manifestations of Crohn’s Disease: A Systematic Review
title_full_unstemmed Oral Manifestations of Crohn’s Disease: A Systematic Review
title_short Oral Manifestations of Crohn’s Disease: A Systematic Review
title_sort oral manifestations of crohn’s disease: a systematic review
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607549/
https://www.ncbi.nlm.nih.gov/pubmed/37892587
http://dx.doi.org/10.3390/jcm12206450
work_keys_str_mv AT peccilloretmariapilar oralmanifestationsofcrohnsdiseaseasystematicreview
AT ramirezsantistebanemma oralmanifestationsofcrohnsdiseaseasystematicreview
AT herguetacastilloadraz oralmanifestationsofcrohnsdiseaseasystematicreview
AT guerrerogironesjulia oralmanifestationsofcrohnsdiseaseasystematicreview
AT onatesanchezricardoelias oralmanifestationsofcrohnsdiseaseasystematicreview