A Therapeutic DNA Vaccine Targeting HPV16 E7 in Combination with Anti-PD-1/PD-L1 Enhanced Tumor Regression and Cytotoxic Immune Responses

Persistent infection of high-risk human papillomavirus (HPV) and the expression of E6 and E7 oncoproteins are the main causes of cervical cancer. Several prophylactic HPV vaccines are used in the clinic, but these vaccines have limited efficacy in patients already infected with HPV. Since HPV E7 is...

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Detalles Bibliográficos
Autores principales: Han, Xuechao, Gao, Zhixiao, Cheng, Yeping, Wu, Shuoshuo, Chen, Jianxing, Zhang, Weifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607554/
https://www.ncbi.nlm.nih.gov/pubmed/37895145
http://dx.doi.org/10.3390/ijms242015469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607554/
https://www.ncbi.nlm.nih.gov/pubmed/37895145
http://dx.doi.org/10.3390/ijms242015469

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