The Effects of Heparan Sulfate Infusion on Endothelial and Organ Injury in a Rat Pneumosepsis Model

Septic shock is characterized by endothelial dysfunction, leading to tissue edema and organ failure. Heparan sulfate (HS) is essential for vascular barrier integrity, possibly via albumin as a carrier. We hypothesized that supplementing fluid resuscitation with HS would improve endothelial barrier f...

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Detalles Bibliográficos
Autores principales: van den Brink, Daan P., Kleinveld, Derek J. B., Bongers, Annabel, Vos, Jaël, Roelofs, Joris T. H., Weber, Nina C., van Buul, Jaap D., Juffermans, Nicole P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607557/
https://www.ncbi.nlm.nih.gov/pubmed/37892576
http://dx.doi.org/10.3390/jcm12206438

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