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Progress in Cardiac Resynchronisation Therapy and Optimisation

Cardiac resynchronisation therapy (CRT) has become the cornerstone of heart failure (HF) treatment. Despite the obvious benefit from this therapy, an estimated 30% of CRT patients do not respond (“non-responders”). The cause of “non-response” is multi-factorial and includes suboptimal device setting...

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Autores principales: Akhtar, Zaki, Gallagher, Mark M., Kontogiannis, Christos, Leung, Lisa W. M., Spartalis, Michael, Jouhra, Fadi, Sohal, Manav, Shanmugam, Nesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607614/
https://www.ncbi.nlm.nih.gov/pubmed/37887875
http://dx.doi.org/10.3390/jcdd10100428
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author Akhtar, Zaki
Gallagher, Mark M.
Kontogiannis, Christos
Leung, Lisa W. M.
Spartalis, Michael
Jouhra, Fadi
Sohal, Manav
Shanmugam, Nesan
author_facet Akhtar, Zaki
Gallagher, Mark M.
Kontogiannis, Christos
Leung, Lisa W. M.
Spartalis, Michael
Jouhra, Fadi
Sohal, Manav
Shanmugam, Nesan
author_sort Akhtar, Zaki
collection PubMed
description Cardiac resynchronisation therapy (CRT) has become the cornerstone of heart failure (HF) treatment. Despite the obvious benefit from this therapy, an estimated 30% of CRT patients do not respond (“non-responders”). The cause of “non-response” is multi-factorial and includes suboptimal device settings. To optimise CRT settings, echocardiography has been considered the gold standard but has limitations: it is user dependent and consumes time and resources. CRT proprietary algorithms have been developed to perform device optimisation efficiently and with limited resources. In this review, we discuss CRT optimisation including the various adopted proprietary algorithms and conduction system pacing.
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spelling pubmed-106076142023-10-28 Progress in Cardiac Resynchronisation Therapy and Optimisation Akhtar, Zaki Gallagher, Mark M. Kontogiannis, Christos Leung, Lisa W. M. Spartalis, Michael Jouhra, Fadi Sohal, Manav Shanmugam, Nesan J Cardiovasc Dev Dis Review Cardiac resynchronisation therapy (CRT) has become the cornerstone of heart failure (HF) treatment. Despite the obvious benefit from this therapy, an estimated 30% of CRT patients do not respond (“non-responders”). The cause of “non-response” is multi-factorial and includes suboptimal device settings. To optimise CRT settings, echocardiography has been considered the gold standard but has limitations: it is user dependent and consumes time and resources. CRT proprietary algorithms have been developed to perform device optimisation efficiently and with limited resources. In this review, we discuss CRT optimisation including the various adopted proprietary algorithms and conduction system pacing. MDPI 2023-10-17 /pmc/articles/PMC10607614/ /pubmed/37887875 http://dx.doi.org/10.3390/jcdd10100428 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Akhtar, Zaki
Gallagher, Mark M.
Kontogiannis, Christos
Leung, Lisa W. M.
Spartalis, Michael
Jouhra, Fadi
Sohal, Manav
Shanmugam, Nesan
Progress in Cardiac Resynchronisation Therapy and Optimisation
title Progress in Cardiac Resynchronisation Therapy and Optimisation
title_full Progress in Cardiac Resynchronisation Therapy and Optimisation
title_fullStr Progress in Cardiac Resynchronisation Therapy and Optimisation
title_full_unstemmed Progress in Cardiac Resynchronisation Therapy and Optimisation
title_short Progress in Cardiac Resynchronisation Therapy and Optimisation
title_sort progress in cardiac resynchronisation therapy and optimisation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607614/
https://www.ncbi.nlm.nih.gov/pubmed/37887875
http://dx.doi.org/10.3390/jcdd10100428
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