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Rhabdomyolysis in a Long-Term Statin User Without Traditional Risk Factors: A Case Report

We report a rare case of rhabdomyolysis in a 64-year-old man who had been receiving long-term statin therapy for hyperlipidemia. The patient initially presented with symptoms of acute appendicitis, which later progressed to acute renal failure and rhabdomyolysis. No commonly identified risk factors...

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Autores principales: Naritaka, Hiroyuki, Aoki, Yoshitaka, Obata, Yukako, Mimuro, Soichiro, Nakajima, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607640/
https://www.ncbi.nlm.nih.gov/pubmed/37900543
http://dx.doi.org/10.7759/cureus.46069
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author Naritaka, Hiroyuki
Aoki, Yoshitaka
Obata, Yukako
Mimuro, Soichiro
Nakajima, Yoshiki
author_facet Naritaka, Hiroyuki
Aoki, Yoshitaka
Obata, Yukako
Mimuro, Soichiro
Nakajima, Yoshiki
author_sort Naritaka, Hiroyuki
collection PubMed
description We report a rare case of rhabdomyolysis in a 64-year-old man who had been receiving long-term statin therapy for hyperlipidemia. The patient initially presented with symptoms of acute appendicitis, which later progressed to acute renal failure and rhabdomyolysis. No commonly identified risk factors for rhabdomyolysis, including drug interactions and statin doses, were observed. The patient was urgently admitted to the intensive care unit where the relevant medications were discontinued in a timely manner and infusion resuscitation was performed. Renal function and serum creatine kinase levels gradually stabilized without the need for hemodialysis. After four days, the patient was transferred to a general ward and was fully discharged from the hospital 13 days after admission. This case highlights the importance of considering rhabdomyolysis as a possible complication among patients receiving statin therapy, even in the absence of traditional risk factors.
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spelling pubmed-106076402023-10-28 Rhabdomyolysis in a Long-Term Statin User Without Traditional Risk Factors: A Case Report Naritaka, Hiroyuki Aoki, Yoshitaka Obata, Yukako Mimuro, Soichiro Nakajima, Yoshiki Cureus Emergency Medicine We report a rare case of rhabdomyolysis in a 64-year-old man who had been receiving long-term statin therapy for hyperlipidemia. The patient initially presented with symptoms of acute appendicitis, which later progressed to acute renal failure and rhabdomyolysis. No commonly identified risk factors for rhabdomyolysis, including drug interactions and statin doses, were observed. The patient was urgently admitted to the intensive care unit where the relevant medications were discontinued in a timely manner and infusion resuscitation was performed. Renal function and serum creatine kinase levels gradually stabilized without the need for hemodialysis. After four days, the patient was transferred to a general ward and was fully discharged from the hospital 13 days after admission. This case highlights the importance of considering rhabdomyolysis as a possible complication among patients receiving statin therapy, even in the absence of traditional risk factors. Cureus 2023-09-27 /pmc/articles/PMC10607640/ /pubmed/37900543 http://dx.doi.org/10.7759/cureus.46069 Text en Copyright © 2023, Naritaka et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Naritaka, Hiroyuki
Aoki, Yoshitaka
Obata, Yukako
Mimuro, Soichiro
Nakajima, Yoshiki
Rhabdomyolysis in a Long-Term Statin User Without Traditional Risk Factors: A Case Report
title Rhabdomyolysis in a Long-Term Statin User Without Traditional Risk Factors: A Case Report
title_full Rhabdomyolysis in a Long-Term Statin User Without Traditional Risk Factors: A Case Report
title_fullStr Rhabdomyolysis in a Long-Term Statin User Without Traditional Risk Factors: A Case Report
title_full_unstemmed Rhabdomyolysis in a Long-Term Statin User Without Traditional Risk Factors: A Case Report
title_short Rhabdomyolysis in a Long-Term Statin User Without Traditional Risk Factors: A Case Report
title_sort rhabdomyolysis in a long-term statin user without traditional risk factors: a case report
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607640/
https://www.ncbi.nlm.nih.gov/pubmed/37900543
http://dx.doi.org/10.7759/cureus.46069
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