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Persistence Pays Off: Live Birth after Uterus Transplant, Overcoming Recurrent Pregnancy Loss with Cerclage Placement
Recipients of uterus transplantation have unique factors that may increase their risk of cervical insufficiency. This report describes a uterus transplant recipient with cervical insufficiency resulting in two second-trimester miscarriages. After McDonald cerclages (one that failed), she underwent a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607750/ https://www.ncbi.nlm.nih.gov/pubmed/37892602 http://dx.doi.org/10.3390/jcm12206463 |
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author | Johannesson, Liza Anderson, Sophie Putman, J. Michael Gunby, Robert T. Zhang, Lilly Testa, Giuliano Gregg, Anthony R. |
author_facet | Johannesson, Liza Anderson, Sophie Putman, J. Michael Gunby, Robert T. Zhang, Lilly Testa, Giuliano Gregg, Anthony R. |
author_sort | Johannesson, Liza |
collection | PubMed |
description | Recipients of uterus transplantation have unique factors that may increase their risk of cervical insufficiency. This report describes a uterus transplant recipient with cervical insufficiency resulting in two second-trimester miscarriages. After McDonald cerclages (one that failed), she underwent an interval transabdominal cerclage and delivered a healthy term child in her third pregnancy. The longitudinal information of this case provides observations from which we can propose testable hypotheses that address venous outflow and inflammation. This case also suggests that there could be a role for prophylactic cerclage placement at the time of transplantation. |
format | Online Article Text |
id | pubmed-10607750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106077502023-10-28 Persistence Pays Off: Live Birth after Uterus Transplant, Overcoming Recurrent Pregnancy Loss with Cerclage Placement Johannesson, Liza Anderson, Sophie Putman, J. Michael Gunby, Robert T. Zhang, Lilly Testa, Giuliano Gregg, Anthony R. J Clin Med Case Report Recipients of uterus transplantation have unique factors that may increase their risk of cervical insufficiency. This report describes a uterus transplant recipient with cervical insufficiency resulting in two second-trimester miscarriages. After McDonald cerclages (one that failed), she underwent an interval transabdominal cerclage and delivered a healthy term child in her third pregnancy. The longitudinal information of this case provides observations from which we can propose testable hypotheses that address venous outflow and inflammation. This case also suggests that there could be a role for prophylactic cerclage placement at the time of transplantation. MDPI 2023-10-11 /pmc/articles/PMC10607750/ /pubmed/37892602 http://dx.doi.org/10.3390/jcm12206463 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Johannesson, Liza Anderson, Sophie Putman, J. Michael Gunby, Robert T. Zhang, Lilly Testa, Giuliano Gregg, Anthony R. Persistence Pays Off: Live Birth after Uterus Transplant, Overcoming Recurrent Pregnancy Loss with Cerclage Placement |
title | Persistence Pays Off: Live Birth after Uterus Transplant, Overcoming Recurrent Pregnancy Loss with Cerclage Placement |
title_full | Persistence Pays Off: Live Birth after Uterus Transplant, Overcoming Recurrent Pregnancy Loss with Cerclage Placement |
title_fullStr | Persistence Pays Off: Live Birth after Uterus Transplant, Overcoming Recurrent Pregnancy Loss with Cerclage Placement |
title_full_unstemmed | Persistence Pays Off: Live Birth after Uterus Transplant, Overcoming Recurrent Pregnancy Loss with Cerclage Placement |
title_short | Persistence Pays Off: Live Birth after Uterus Transplant, Overcoming Recurrent Pregnancy Loss with Cerclage Placement |
title_sort | persistence pays off: live birth after uterus transplant, overcoming recurrent pregnancy loss with cerclage placement |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607750/ https://www.ncbi.nlm.nih.gov/pubmed/37892602 http://dx.doi.org/10.3390/jcm12206463 |
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