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Quaternary Benzophenanthridine Alkaloids Act as Smac Mimetics and Overcome Resistance to Apoptosis

Defects in cell death signaling pathways are one of the hallmarks of cancer and can lead to resistance to conventional therapy. Natural products are promising compounds that can overcome this resistance. In the present study we studied the effect of six quaternary benzophenanthridine alkaloids (QBAs...

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Detalles Bibliográficos
Autores principales: Kulíšková, Petra, Vašátková, Lucie, Slaninová, Iva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607862/
https://www.ncbi.nlm.nih.gov/pubmed/37895085
http://dx.doi.org/10.3390/ijms242015405