Cargando…

Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program

Childhood obesity represents a significant challenge both clinically and socio-economically. This study aimed to assess specific biochemical parameters, particularly glucose, insulin and lipid profile, before and after a year-long intervention program in 8- and 9-year-old children with excessive bod...

Descripción completa

Detalles Bibliográficos
Autores principales: Raducha, Dominika, Ratajczak, Joanna, Kostrzeba, Ewa, Berus, Ewa, Walczak, Mieczysław, Petriczko, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607870/
https://www.ncbi.nlm.nih.gov/pubmed/37892696
http://dx.doi.org/10.3390/jcm12206560
_version_ 1785127645169582080
author Raducha, Dominika
Ratajczak, Joanna
Kostrzeba, Ewa
Berus, Ewa
Walczak, Mieczysław
Petriczko, Elżbieta
author_facet Raducha, Dominika
Ratajczak, Joanna
Kostrzeba, Ewa
Berus, Ewa
Walczak, Mieczysław
Petriczko, Elżbieta
author_sort Raducha, Dominika
collection PubMed
description Childhood obesity represents a significant challenge both clinically and socio-economically. This study aimed to assess specific biochemical parameters, particularly glucose, insulin and lipid profile, before and after a year-long intervention program in 8- and 9-year-old children with excessive body weight living in Szczecin, Poland from 2016 to 2018. The research comprised two phases: screening in elementary schools and intervention in the outpatient clinic of the clinical Pomeranian Medical University hospital. Out of 11,494 8- to 9-year-olds in Szczecin, 42.54% (4890) participated in the screening. In the intervention phase, 515 children were examined. Anthropometric measurements were recorded at each visit, and blood samples were collected during the first and fourth visits. In the statistical analysis, the Kolmogorov–Smirnov, t-Student and ANOVA tests were employed (with statistical significance when p ≤ 0.05). Results highlighted a significant proportion of children exhibiting disruptions in carbohydrate and lipid metabolism. A total of 8.6% of participants had elevated total cholesterol, 9.7% had reduced HDL, 13.4% had elevated LDL, and 21.2% had elevated triglycerides. Initially, abnormal fasting glucose was detected in 4.7% of children, and elevated insulin levels in 3.1%. Metabolic disorders persisted post-intervention despite BMI improvement. The results emphasize the necessity for prolonged programs with frequent follow-ups targeting weight normalization in children.
format Online
Article
Text
id pubmed-10607870
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-106078702023-10-28 Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program Raducha, Dominika Ratajczak, Joanna Kostrzeba, Ewa Berus, Ewa Walczak, Mieczysław Petriczko, Elżbieta J Clin Med Article Childhood obesity represents a significant challenge both clinically and socio-economically. This study aimed to assess specific biochemical parameters, particularly glucose, insulin and lipid profile, before and after a year-long intervention program in 8- and 9-year-old children with excessive body weight living in Szczecin, Poland from 2016 to 2018. The research comprised two phases: screening in elementary schools and intervention in the outpatient clinic of the clinical Pomeranian Medical University hospital. Out of 11,494 8- to 9-year-olds in Szczecin, 42.54% (4890) participated in the screening. In the intervention phase, 515 children were examined. Anthropometric measurements were recorded at each visit, and blood samples were collected during the first and fourth visits. In the statistical analysis, the Kolmogorov–Smirnov, t-Student and ANOVA tests were employed (with statistical significance when p ≤ 0.05). Results highlighted a significant proportion of children exhibiting disruptions in carbohydrate and lipid metabolism. A total of 8.6% of participants had elevated total cholesterol, 9.7% had reduced HDL, 13.4% had elevated LDL, and 21.2% had elevated triglycerides. Initially, abnormal fasting glucose was detected in 4.7% of children, and elevated insulin levels in 3.1%. Metabolic disorders persisted post-intervention despite BMI improvement. The results emphasize the necessity for prolonged programs with frequent follow-ups targeting weight normalization in children. MDPI 2023-10-16 /pmc/articles/PMC10607870/ /pubmed/37892696 http://dx.doi.org/10.3390/jcm12206560 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Raducha, Dominika
Ratajczak, Joanna
Kostrzeba, Ewa
Berus, Ewa
Walczak, Mieczysław
Petriczko, Elżbieta
Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program
title Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program
title_full Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program
title_fullStr Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program
title_full_unstemmed Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program
title_short Assessment of Biochemical Parameters in 8- and 9-Year-Old Children with Excessive Body Weight Participating in a Year-Long Intervention Program
title_sort assessment of biochemical parameters in 8- and 9-year-old children with excessive body weight participating in a year-long intervention program
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607870/
https://www.ncbi.nlm.nih.gov/pubmed/37892696
http://dx.doi.org/10.3390/jcm12206560
work_keys_str_mv AT raduchadominika assessmentofbiochemicalparametersin8and9yearoldchildrenwithexcessivebodyweightparticipatinginayearlonginterventionprogram
AT ratajczakjoanna assessmentofbiochemicalparametersin8and9yearoldchildrenwithexcessivebodyweightparticipatinginayearlonginterventionprogram
AT kostrzebaewa assessmentofbiochemicalparametersin8and9yearoldchildrenwithexcessivebodyweightparticipatinginayearlonginterventionprogram
AT berusewa assessmentofbiochemicalparametersin8and9yearoldchildrenwithexcessivebodyweightparticipatinginayearlonginterventionprogram
AT walczakmieczysław assessmentofbiochemicalparametersin8and9yearoldchildrenwithexcessivebodyweightparticipatinginayearlonginterventionprogram
AT petriczkoelzbieta assessmentofbiochemicalparametersin8and9yearoldchildrenwithexcessivebodyweightparticipatinginayearlonginterventionprogram