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Phenylacetyl-/Trolox- Amides: Synthesis, Sigma-1, HDAC-6, and Antioxidant Activities

In search of novel multi-mechanistic approaches for treating Alzheimer’s disease (AD), we have embarked on synthesizing single small molecules for probing contributory roles of the following combined disease targets: sigma-1 (σ-1), class IIb histone deacetylase-6 (HDAC-6), and oxidative stress (OS)....

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Detalles Bibliográficos
Autores principales:	Flores, Rafael, Iqbal, Shoaib, Sikazwe, Donald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10607876/ https://www.ncbi.nlm.nih.gov/pubmed/37894975 http://dx.doi.org/10.3390/ijms242015295

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