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Early and Late Complications after Cataract Surgery in Patients with Uveitis

Background and Objectives: Uveitis, a prevalent eye disorder characterized by inflammatory processes, often leads to cataract formation and significant visual impairment. This study aimed to evaluate preoperative conditions and postoperative outcomes following cataract surgery in uveitis patients. M...

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Autores principales: Bajraktari, Gentian, Jukić, Tomislav, Kalauz, Miro, Oroz, Martin, Radolović Bertetić, Andrea, Vukojević, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608233/
https://www.ncbi.nlm.nih.gov/pubmed/37893595
http://dx.doi.org/10.3390/medicina59101877
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author Bajraktari, Gentian
Jukić, Tomislav
Kalauz, Miro
Oroz, Martin
Radolović Bertetić, Andrea
Vukojević, Nenad
author_facet Bajraktari, Gentian
Jukić, Tomislav
Kalauz, Miro
Oroz, Martin
Radolović Bertetić, Andrea
Vukojević, Nenad
author_sort Bajraktari, Gentian
collection PubMed
description Background and Objectives: Uveitis, a prevalent eye disorder characterized by inflammatory processes, often leads to cataract formation and significant visual impairment. This study aimed to evaluate preoperative conditions and postoperative outcomes following cataract surgery in uveitis patients. Materials and Methods: A retrospective study was conducted at the University Hospital Center Rebro Zagreb, Croatia, involving uveitis patients who underwent cataract surgery between 2013 and 2022. Eligible patients had uveitic cataracts affecting visual acuity or posterior segment visualization in a “quiet eye” and were disease-inactive for at least three months. Patients with certain pre-existing ocular conditions were excluded. The data collected included patient demographics, uveitis type, preoperative therapy, preexisting lesions, and postoperative outcomes such as visual acuity, intraocular pressure, central macular thickness, and complications. Statistical analysis was performed to identify risk factors associated with complications. Results: This study included 105 patients. The most common uveitis types were idiopathic uveitis, HLA-B27-associated uveitis, and JIA uveitis. After cataract surgery, there was a significant improvement in visual acuity at various time points, with 90% of eyes showing improvement. Intraocular pressure decreased over time. Central macular thickness increased at three months post-surgery but remained stable thereafter. Early and late complications were observed in 52.4% and 63.8% of eyes, respectively. The most common complications were posterior capsular opacification (53.3%), macular edema (26.6%), and epiretinal membrane formation (9.52%). The factors associated with complications varied between early and late stages but included age, age at the onset of uveitis, and the uveitis type. Conclusions: In patients with quiescent uveitis undergoing cataract surgery, significant visual improvement was achieved. This study highlights the importance of careful patient selection, preoperative and postoperative inflammation management, and precise surgical techniques. Although complications were common, the risk of capsular opacification, macular edema, and epiretinal membrane formation after surgery increased. However, future investigations should address this study’s limitations and further refine perioperative strategies.
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spelling pubmed-106082332023-10-28 Early and Late Complications after Cataract Surgery in Patients with Uveitis Bajraktari, Gentian Jukić, Tomislav Kalauz, Miro Oroz, Martin Radolović Bertetić, Andrea Vukojević, Nenad Medicina (Kaunas) Article Background and Objectives: Uveitis, a prevalent eye disorder characterized by inflammatory processes, often leads to cataract formation and significant visual impairment. This study aimed to evaluate preoperative conditions and postoperative outcomes following cataract surgery in uveitis patients. Materials and Methods: A retrospective study was conducted at the University Hospital Center Rebro Zagreb, Croatia, involving uveitis patients who underwent cataract surgery between 2013 and 2022. Eligible patients had uveitic cataracts affecting visual acuity or posterior segment visualization in a “quiet eye” and were disease-inactive for at least three months. Patients with certain pre-existing ocular conditions were excluded. The data collected included patient demographics, uveitis type, preoperative therapy, preexisting lesions, and postoperative outcomes such as visual acuity, intraocular pressure, central macular thickness, and complications. Statistical analysis was performed to identify risk factors associated with complications. Results: This study included 105 patients. The most common uveitis types were idiopathic uveitis, HLA-B27-associated uveitis, and JIA uveitis. After cataract surgery, there was a significant improvement in visual acuity at various time points, with 90% of eyes showing improvement. Intraocular pressure decreased over time. Central macular thickness increased at three months post-surgery but remained stable thereafter. Early and late complications were observed in 52.4% and 63.8% of eyes, respectively. The most common complications were posterior capsular opacification (53.3%), macular edema (26.6%), and epiretinal membrane formation (9.52%). The factors associated with complications varied between early and late stages but included age, age at the onset of uveitis, and the uveitis type. Conclusions: In patients with quiescent uveitis undergoing cataract surgery, significant visual improvement was achieved. This study highlights the importance of careful patient selection, preoperative and postoperative inflammation management, and precise surgical techniques. Although complications were common, the risk of capsular opacification, macular edema, and epiretinal membrane formation after surgery increased. However, future investigations should address this study’s limitations and further refine perioperative strategies. MDPI 2023-10-23 /pmc/articles/PMC10608233/ /pubmed/37893595 http://dx.doi.org/10.3390/medicina59101877 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bajraktari, Gentian
Jukić, Tomislav
Kalauz, Miro
Oroz, Martin
Radolović Bertetić, Andrea
Vukojević, Nenad
Early and Late Complications after Cataract Surgery in Patients with Uveitis
title Early and Late Complications after Cataract Surgery in Patients with Uveitis
title_full Early and Late Complications after Cataract Surgery in Patients with Uveitis
title_fullStr Early and Late Complications after Cataract Surgery in Patients with Uveitis
title_full_unstemmed Early and Late Complications after Cataract Surgery in Patients with Uveitis
title_short Early and Late Complications after Cataract Surgery in Patients with Uveitis
title_sort early and late complications after cataract surgery in patients with uveitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608233/
https://www.ncbi.nlm.nih.gov/pubmed/37893595
http://dx.doi.org/10.3390/medicina59101877
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