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The Impact of Age on the Physiological Assessment of Borderline Coronary Stenoses
Background and Objectives: Coronary angiography is the gold standard for diagnosing coronary artery disease (CAD). In the case of borderline changes, patients require further diagnosis through ischemia assessment via one of the recommended methods of invasive evaluation. This study aimed to assess w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608417/ https://www.ncbi.nlm.nih.gov/pubmed/37893581 http://dx.doi.org/10.3390/medicina59101863 |
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author | Zasada, Wojciech Zdzierak, Barbara Rakowski, Tomasz Bobrowska, Beata Krawczyk-Ożóg, Agata Surowiec, Sławomir Bartuś, Stanisław Surdacki, Andrzej Dziewierz, Artur |
author_facet | Zasada, Wojciech Zdzierak, Barbara Rakowski, Tomasz Bobrowska, Beata Krawczyk-Ożóg, Agata Surowiec, Sławomir Bartuś, Stanisław Surdacki, Andrzej Dziewierz, Artur |
author_sort | Zasada, Wojciech |
collection | PubMed |
description | Background and Objectives: Coronary angiography is the gold standard for diagnosing coronary artery disease (CAD). In the case of borderline changes, patients require further diagnosis through ischemia assessment via one of the recommended methods of invasive evaluation. This study aimed to assess whether clinical factors influence the risk of a positive result in invasive myocardial ischemia assessment and if these potential factors change with the patient’s age and the consistency of ischemia assessment. Materials and Methods: Data were collected retrospectively on all consecutive patients hospitalized in the University Hospital in Krakow between 2020 and 2021, on whom physiological assessments of coronary circulation were performed. Patients were divided into two groups: patients aged 60 or younger and patients older than 60. Results: Despite the older patients having more risk factors for CAD, their physiological assessment results of borderline lesions were similar to those of the younger patients. Positive fractional flow reserve (FFR) assessments were obtained from almost 50% of vessels. In the younger patients, cigarette use and type 2 diabetes mellitus increased the risk of a positive FFR result by 3.5 and 2.5 times, respectively. In the older patients, male gender and peripheral vascular disease significantly increased the risk of a positive FFR by 2.5 and 2 times, respectively. Conclusions: Clinical characteristics of patients undergoing physiological assessment of borderline coronary stenosis varied significantly by age. Refining the definition of borderline lesions to include age, gender, and other factors may improve the identification of patients who would benefit from physiological assessment and coronary revascularization. |
format | Online Article Text |
id | pubmed-10608417 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106084172023-10-28 The Impact of Age on the Physiological Assessment of Borderline Coronary Stenoses Zasada, Wojciech Zdzierak, Barbara Rakowski, Tomasz Bobrowska, Beata Krawczyk-Ożóg, Agata Surowiec, Sławomir Bartuś, Stanisław Surdacki, Andrzej Dziewierz, Artur Medicina (Kaunas) Article Background and Objectives: Coronary angiography is the gold standard for diagnosing coronary artery disease (CAD). In the case of borderline changes, patients require further diagnosis through ischemia assessment via one of the recommended methods of invasive evaluation. This study aimed to assess whether clinical factors influence the risk of a positive result in invasive myocardial ischemia assessment and if these potential factors change with the patient’s age and the consistency of ischemia assessment. Materials and Methods: Data were collected retrospectively on all consecutive patients hospitalized in the University Hospital in Krakow between 2020 and 2021, on whom physiological assessments of coronary circulation were performed. Patients were divided into two groups: patients aged 60 or younger and patients older than 60. Results: Despite the older patients having more risk factors for CAD, their physiological assessment results of borderline lesions were similar to those of the younger patients. Positive fractional flow reserve (FFR) assessments were obtained from almost 50% of vessels. In the younger patients, cigarette use and type 2 diabetes mellitus increased the risk of a positive FFR result by 3.5 and 2.5 times, respectively. In the older patients, male gender and peripheral vascular disease significantly increased the risk of a positive FFR by 2.5 and 2 times, respectively. Conclusions: Clinical characteristics of patients undergoing physiological assessment of borderline coronary stenosis varied significantly by age. Refining the definition of borderline lesions to include age, gender, and other factors may improve the identification of patients who would benefit from physiological assessment and coronary revascularization. MDPI 2023-10-19 /pmc/articles/PMC10608417/ /pubmed/37893581 http://dx.doi.org/10.3390/medicina59101863 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zasada, Wojciech Zdzierak, Barbara Rakowski, Tomasz Bobrowska, Beata Krawczyk-Ożóg, Agata Surowiec, Sławomir Bartuś, Stanisław Surdacki, Andrzej Dziewierz, Artur The Impact of Age on the Physiological Assessment of Borderline Coronary Stenoses |
title | The Impact of Age on the Physiological Assessment of Borderline Coronary Stenoses |
title_full | The Impact of Age on the Physiological Assessment of Borderline Coronary Stenoses |
title_fullStr | The Impact of Age on the Physiological Assessment of Borderline Coronary Stenoses |
title_full_unstemmed | The Impact of Age on the Physiological Assessment of Borderline Coronary Stenoses |
title_short | The Impact of Age on the Physiological Assessment of Borderline Coronary Stenoses |
title_sort | impact of age on the physiological assessment of borderline coronary stenoses |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608417/ https://www.ncbi.nlm.nih.gov/pubmed/37893581 http://dx.doi.org/10.3390/medicina59101863 |
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