Cargando…

Esculeoside A Decreases Diabetic Cardiomyopathy in Streptozotocin-Treated Rats by Attenuating Oxidative Stress, Inflammation, Fibrosis, and Apoptosis: Impressive Role of Nrf2

Background and Objectives: This experiment evaluated the preventative influence of the tomato-derived Esculeoside A (ESA) on diabetic cardiomyopathy in type 1 diabetes mellitus (T1DM) in rats induced by streptozotocin (STZ). It also examined whether the activation of Nrf2 signaling affords this prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	ALTamimi, Jozaa Z., AlFaris, Nora A., Alshammari, Ghedeir M., Alagal, Reham I., Aljabryn, Dalal H., Yahya, Mohammed Abdo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608477/ https://www.ncbi.nlm.nih.gov/pubmed/37893548 http://dx.doi.org/10.3390/medicina59101830

Ejemplares similares

Esculeoside A alleviates reproductive toxicity in streptozotocin-diabetic rats’ s model by activating Nrf2 signaling
por: AlTamimi, Jozaa Z., et al.
Publicado: (2023)

Protective effect of eriodictyol against hyperglycemia-induced diabetic nephropathy in rats entails antioxidant and anti-inflammatory effects mediated by activating Nrf2
por: AlTamimi, Jozaa Z., et al.
Publicado: (2023)

The Protective Effect of 11-Keto-β-Boswellic Acid against Diabetic Cardiomyopathy in Rats Entails Activation of AMPK
por: AlTamimi, Jozaa Z., et al.
Publicado: (2023)

Ellagic acid improved diabetes mellitus-induced testicular damage and sperm abnormalities by activation of Nrf2
por: ALTamimi, Jozaa Z., et al.
Publicado: (2021)

Ellagic acid protects against non-alcoholic fatty liver disease in streptozotocin-diabetic rats by activating AMPK
por: ALTamimi, Jozaa Z., et al.
Publicado: (2021)

Rumex nervosus could alleviate streptozotocin-induced diabetic nephropathy in rats by activating Nrf2 signaling
por: AlMousa, Lujain A, et al.
Publicado: (2022)

Evaluating the effects of different processing methods on the nutritional composition of shrimp and the antioxidant activity of shrimp powder
por: AlFaris, Nora A., et al.
Publicado: (2022)

The protective effect of shrimp cooked in different methods on high-cholesterol- induced fatty liver in rats
por: AlFaris, Nora A., et al.
Publicado: (2021)

Antioxidant and antimicrobial potential of two extracts from Capparis spinosa L. and Rumex nervosus and molecular docking investigation of selected major compounds
por: AlMousa, Lujain A., et al.
Publicado: (2022)

Fisetin protects against streptozotocin-induced diabetic cardiomyopathy in rats by suppressing fatty acid oxidation and inhibiting protein kinase R
por: ALTamimi, Jozaa Z., et al.
Publicado: (2021)

Antidiabetic and antihyperlipidemic effect of Duvalia corderoyi in rats with streptozotocin-induced diabetes
por: AlFaris, Nora A., et al.
Publicado: (2020)

Breakfast Skipping in a Multi-Ethnic Population of Middle-Aged Men and Relationship With Sociodemographic Variables and Weight Status
por: AlFaris, Nora A., et al.
Publicado: (2022)

Breakfast Skipping among a Multi-Ethnic Population of Young Men and Relationship with Sociodemographic Determinants and Weight Status
por: AlTamimi, Jozaa Z., et al.
Publicado: (2022)

Differences in Overweight and Obesity Prevalence in Middle-Aged Men from Twelve Middle Eastern and Asian Countries Living in Saudi Arabia
por: AlTamimi, Jozaa Z, et al.
Publicado: (2022)

Physical Activity Levels of a Multi-Ethnic Population of Young Men Living in Saudi Arabia and Factors Associated With Physical Inactivity
por: AlTamimi, Jozaa Z., et al.
Publicado: (2022)

Physical Activity Levels of a Multi-Ethnic Population of Middle-Aged Men Living in Saudi Arabia and Factors Associated With Physical Inactivity
por: AlFaris, Nora A., et al.
Publicado: (2022)

Differences in Overweight and Obesity Prevalence among Young Men from Twelve Middle Eastern and Asian Countries Living in Saudi Arabia
por: Alagal, Reham I., et al.
Publicado: (2022)

Prevalence of Fast Food Intake among a Multi-Ethnic Population of Young Men and Its Connection with Sociodemographic Determinants and Obesity
por: AlTamimi, Jozaa Z., et al.
Publicado: (2022)

Prevalence of fast-food intake among a multi-ethnic population of middle-aged men and connection with sociodemographic factors and obesity
por: AlTamimi, Jozaa Z., et al.
Publicado: (2023)

Total phenolic content in ripe date fruits (Phoenix dactylifera L.): A systematic review and meta-analysis
por: AlFaris, Nora Abdullah, et al.
Publicado: (2021)

Sugar-sweetened beverages consumption in a multi-ethnic population of middle-aged men and association with sociodemographic variables and obesity
por: AlFaris, Nora A., et al.
Publicado: (2022)

Sugar-Sweetened Beverages Consumption in a Multi-Ethnic Population of Young Men and Association with Sociodemographic Characteristics and Obesity
por: AlTamimi, Jozaa Z., et al.
Publicado: (2023)

Validation of low dosages of γ-radiation and their effect on red beetle mortality, storability characteristics, and nutritional value of sorghum (Sorghum bicolor L. Moench) grain
por: Hassan, Amro B., et al.
Publicado: (2023)

Phloretamide Prevent Hepatic and Pancreatic Damage in Diabetic Male Rats by Modulating Nrf2 and NF-κB
por: Al-Hussan, Rasha, et al.
Publicado: (2023)

Evaluation and Comparison of the Nutritional and Mineral Content of Milk Formula in the Saudi Arabia Market
por: Alfaris, Nora A., et al.
Publicado: (2022)

Hypoglycemic effects of esculeoside A are mediated via activation of AMPK and upregulation of IRS-1
por: Yang, Ziming, et al.
Publicado: (2019)

The Protective Effect of α-Lipoic Acid against Gold Nanoparticles (AuNPs)-Mediated Liver Damage Is Associated with Upregulating Nrf2 and Suppressing NF-κB
por: Alshammari, Ghedeir M., et al.
Publicado: (2022)

Identification of potent food constituents as SARS-CoV-2 papain-like protease modulators through advanced pharmacoinformatics approaches
por: Bhowmick, Shovonlal, et al.
Publicado: (2022)

Identification of bio-active food compounds as potential SARS-CoV-2 PLpro inhibitors-modulators via negative image-based screening and computational simulations
por: Bhowmick, Shovonlal, et al.
Publicado: (2022)

Structure-based identification of galectin-1 selective modulators in dietary food polyphenols: a pharmacoinformatics approach
por: Bhowmick, Shovonlal, et al.
Publicado: (2021)

Decrease of Hyaluronidase Activity and Suppression of Mouse CD4+ T Lymphocyte Activation by Tomato Juice Saponin Esculeoside B, and Its Sapogenol Esculeogenin B
por: Zhou, Jian-Rong, et al.
Publicado: (2022)

Moringa peregrina leaf extracts produce anti-obesity, hypoglycemic, anti-hyperlipidemic, and hepatoprotective effects on high-fat diet fed rats
por: Alkhudhayri, Dalal A., et al.
Publicado: (2021)

Chitosan-Coated Solid Lipid Nanoparticles as an Efficient Avenue for Boosted Biological Activities of Aloe perryi: Antioxidant, Antibacterial, and Anticancer Potential
por: Aldayel, Tahany Saleh, et al.
Publicado: (2023)

Prevalence of Anemia and Associated Risk Factors Among Non-Pregnant Women in Riyadh, Saudi Arabia: A Cross-Sectional Study
por: AlFaris, Nora, et al.
Publicado: (2021)

KLF9 Aggravates Streptozotocin-Induced Diabetic Cardiomyopathy by Inhibiting PPARγ/NRF2 Signalling
por: Li, Fangfang, et al.
Publicado: (2022)

Nutritional Status of Saudi Children with Celiac Disease Following the Ministry of Health’s Gluten-Free Diet Program
por: Allowaymi, Shiekhah S., et al.
Publicado: (2022)

Effects of Antioxidant Combinations on the Renal Toxicity Induced Rats by Gold Nanoparticles
por: Alshammari, Ghedeir M., et al.
Publicado: (2023)

Concomitant Sub-Chronic Administration of Small-Size Gold Nanoparticles Aggravates Doxorubicin-Induced Liver Oxidative and Inflammatory Damage, Hyperlipidemia, and Hepatic Steatosis
por: Alshammari, Ghedeir M., et al.
Publicado: (2023)

Awareness of the Consumption of Dietary Supplements among Students in a University in Saudi Arabia
por: AlTamimi, Jozaa Z.
Publicado: (2019)

Trends of fast food consumption among adolescent and young adult Saudi girls living in Riyadh
por: ALFaris, Nora A., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vv7hp06faov0ns2u0r0oqntnpv