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Prehospital Predictors of Survival in Patients with Out-of-Hospital Cardiac Arrest

Background and Objectives: Despite advances in the treatment of heart diseases, the outcome of patients experiencing sudden cardiac arrest remains poor. The aim of our study was to determine the prehospital variables as predictors of survival outcomes in out-of-hospital cardiac arrest (OHCA) victims...

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Autores principales: Strnad, Matej, Borovnik Lesjak, Vesna, Jerot, Pia, Esih, Maruša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608532/
https://www.ncbi.nlm.nih.gov/pubmed/37893434
http://dx.doi.org/10.3390/medicina59101717
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author Strnad, Matej
Borovnik Lesjak, Vesna
Jerot, Pia
Esih, Maruša
author_facet Strnad, Matej
Borovnik Lesjak, Vesna
Jerot, Pia
Esih, Maruša
author_sort Strnad, Matej
collection PubMed
description Background and Objectives: Despite advances in the treatment of heart diseases, the outcome of patients experiencing sudden cardiac arrest remains poor. The aim of our study was to determine the prehospital variables as predictors of survival outcomes in out-of-hospital cardiac arrest (OHCA) victims. Materials and Methods: This was a retrospective observational cohort study of OHCA cases. EMS protocols created in accordance with the Utstein style reporting for OHCA, first responder intervention reports, medical dispatch center dispatch protocols and hospital medical reports were all reviewed. Multivariate logistic regression was performed with the following variables: age, gender, witnessed status, location, bystander CPR, first rhythm, and etiology. Results: A total of 381 interventions with resuscitation attempts were analyzed. In more than half (55%) of them, bystander CPR was performed. Thirty percent of all patients achieved return of spontaneous circulation (ROSC), 22% of those achieved 30-day survival (7% of all OHCA victims), and 73% of those survived with Cerebral Performance Score 1 or 2. The logistic regression model of adjustment confirms that shockable initial rhythm was a predictor of ROSC [OR: 4.5 (95% CI: 2.5–8.1)] and 30-day survival [OR: 9.3 (95% CI: 2.9–29.2)]. Age was also associated (≤67 years) [OR: 3.9 (95% CI: 1.3–11.9)] with better survival. Conclusions: Elderly patients have a lower survival rate. The occurrence of bystander CPR in cardiac arrest remains alarmingly low. Shockable initial rhythm is associated with a better survival rate and neurological outcome compared with non-shockable rhythm.
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spelling pubmed-106085322023-10-28 Prehospital Predictors of Survival in Patients with Out-of-Hospital Cardiac Arrest Strnad, Matej Borovnik Lesjak, Vesna Jerot, Pia Esih, Maruša Medicina (Kaunas) Article Background and Objectives: Despite advances in the treatment of heart diseases, the outcome of patients experiencing sudden cardiac arrest remains poor. The aim of our study was to determine the prehospital variables as predictors of survival outcomes in out-of-hospital cardiac arrest (OHCA) victims. Materials and Methods: This was a retrospective observational cohort study of OHCA cases. EMS protocols created in accordance with the Utstein style reporting for OHCA, first responder intervention reports, medical dispatch center dispatch protocols and hospital medical reports were all reviewed. Multivariate logistic regression was performed with the following variables: age, gender, witnessed status, location, bystander CPR, first rhythm, and etiology. Results: A total of 381 interventions with resuscitation attempts were analyzed. In more than half (55%) of them, bystander CPR was performed. Thirty percent of all patients achieved return of spontaneous circulation (ROSC), 22% of those achieved 30-day survival (7% of all OHCA victims), and 73% of those survived with Cerebral Performance Score 1 or 2. The logistic regression model of adjustment confirms that shockable initial rhythm was a predictor of ROSC [OR: 4.5 (95% CI: 2.5–8.1)] and 30-day survival [OR: 9.3 (95% CI: 2.9–29.2)]. Age was also associated (≤67 years) [OR: 3.9 (95% CI: 1.3–11.9)] with better survival. Conclusions: Elderly patients have a lower survival rate. The occurrence of bystander CPR in cardiac arrest remains alarmingly low. Shockable initial rhythm is associated with a better survival rate and neurological outcome compared with non-shockable rhythm. MDPI 2023-09-26 /pmc/articles/PMC10608532/ /pubmed/37893434 http://dx.doi.org/10.3390/medicina59101717 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Strnad, Matej
Borovnik Lesjak, Vesna
Jerot, Pia
Esih, Maruša
Prehospital Predictors of Survival in Patients with Out-of-Hospital Cardiac Arrest
title Prehospital Predictors of Survival in Patients with Out-of-Hospital Cardiac Arrest
title_full Prehospital Predictors of Survival in Patients with Out-of-Hospital Cardiac Arrest
title_fullStr Prehospital Predictors of Survival in Patients with Out-of-Hospital Cardiac Arrest
title_full_unstemmed Prehospital Predictors of Survival in Patients with Out-of-Hospital Cardiac Arrest
title_short Prehospital Predictors of Survival in Patients with Out-of-Hospital Cardiac Arrest
title_sort prehospital predictors of survival in patients with out-of-hospital cardiac arrest
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608532/
https://www.ncbi.nlm.nih.gov/pubmed/37893434
http://dx.doi.org/10.3390/medicina59101717
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