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Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane

Microfluidic devices have gained subsequent attention due to their controlled manipulation of fluid for various biomedical applications. These devices can be used to study the behavior of fluid under several micrometer ranges within the channel. The major applications are the filtration of fluid, bl...

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Autores principales: Qasim, Faheem, Ashraf, Muhammad Waseem, Tayyaba, Shahzadi, Tariq, Muhammad Imran, Herrera-May, Agustín L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608613/
https://www.ncbi.nlm.nih.gov/pubmed/37887997
http://dx.doi.org/10.3390/membranes13100825
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author Qasim, Faheem
Ashraf, Muhammad Waseem
Tayyaba, Shahzadi
Tariq, Muhammad Imran
Herrera-May, Agustín L.
author_facet Qasim, Faheem
Ashraf, Muhammad Waseem
Tayyaba, Shahzadi
Tariq, Muhammad Imran
Herrera-May, Agustín L.
author_sort Qasim, Faheem
collection PubMed
description Microfluidic devices have gained subsequent attention due to their controlled manipulation of fluid for various biomedical applications. These devices can be used to study the behavior of fluid under several micrometer ranges within the channel. The major applications are the filtration of fluid, blood filtration and bio-medical analysis. For the filtration of water, as well as other liquids, the micro-filtration based microfluidic devices are considered as potential candidates to fulfill the desired conditions and requirements. The micro pore membrane can be designed and fabricated in such a way that it maximizes the removal of impurities from fluid. The low-cost micro-filtration method has been reported to provide clean fluid for biomedical applications and other purposes. In the work, anodic-aluminum-oxide-based membranes have been fabricated with different pore sizes ranging from 70 to 500 nm. A soft computing technique like fuzzy logic has been used to estimate the filtration parameters. Then, the finite-element-based analysis system software has been used to study the fluid flow through the double membrane. Then, filtration is performed by using a dual membrane and the clogging of the membrane has been studied after different filtration cycles using characterization like a scanning electron microscope. The filtration has been done to purify the contaminated fluid which has impurities like bacteria and protozoans. The membranes have been tested after each cycle to verify the results. The decrease in permeance with respect to the increase in the velocity of the fluid and the permeate volume per unit clearly depicts the removal of containments from the fluid after four and eight cycles of filtration. The results clearly show that the filtration efficiency can be improved by increasing the number of cycles and adding a dual membrane in the micro-fluidic device. The results show the potential of dual anodic aluminum oxide membranes for the effective filtration of fluids for biomedical applications, thereby offering a promising solution to address current challenges.
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spelling pubmed-106086132023-10-28 Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane Qasim, Faheem Ashraf, Muhammad Waseem Tayyaba, Shahzadi Tariq, Muhammad Imran Herrera-May, Agustín L. Membranes (Basel) Article Microfluidic devices have gained subsequent attention due to their controlled manipulation of fluid for various biomedical applications. These devices can be used to study the behavior of fluid under several micrometer ranges within the channel. The major applications are the filtration of fluid, blood filtration and bio-medical analysis. For the filtration of water, as well as other liquids, the micro-filtration based microfluidic devices are considered as potential candidates to fulfill the desired conditions and requirements. The micro pore membrane can be designed and fabricated in such a way that it maximizes the removal of impurities from fluid. The low-cost micro-filtration method has been reported to provide clean fluid for biomedical applications and other purposes. In the work, anodic-aluminum-oxide-based membranes have been fabricated with different pore sizes ranging from 70 to 500 nm. A soft computing technique like fuzzy logic has been used to estimate the filtration parameters. Then, the finite-element-based analysis system software has been used to study the fluid flow through the double membrane. Then, filtration is performed by using a dual membrane and the clogging of the membrane has been studied after different filtration cycles using characterization like a scanning electron microscope. The filtration has been done to purify the contaminated fluid which has impurities like bacteria and protozoans. The membranes have been tested after each cycle to verify the results. The decrease in permeance with respect to the increase in the velocity of the fluid and the permeate volume per unit clearly depicts the removal of containments from the fluid after four and eight cycles of filtration. The results clearly show that the filtration efficiency can be improved by increasing the number of cycles and adding a dual membrane in the micro-fluidic device. The results show the potential of dual anodic aluminum oxide membranes for the effective filtration of fluids for biomedical applications, thereby offering a promising solution to address current challenges. MDPI 2023-10-08 /pmc/articles/PMC10608613/ /pubmed/37887997 http://dx.doi.org/10.3390/membranes13100825 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Qasim, Faheem
Ashraf, Muhammad Waseem
Tayyaba, Shahzadi
Tariq, Muhammad Imran
Herrera-May, Agustín L.
Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane
title Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane
title_full Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane
title_fullStr Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane
title_full_unstemmed Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane
title_short Simulation, Fabrication and Microfiltration Using Dual Anodic Aluminum Oxide Membrane
title_sort simulation, fabrication and microfiltration using dual anodic aluminum oxide membrane
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608613/
https://www.ncbi.nlm.nih.gov/pubmed/37887997
http://dx.doi.org/10.3390/membranes13100825
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