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4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications
Four-dimensional (4D) printing is an innovative additive manufacturing technology used to fabricate structures that can evolve over time when exposed to a predefined environmental stimulus. 4D printed objects are no longer static objects but programmable active structures that accomplish their funct...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608699/ https://www.ncbi.nlm.nih.gov/pubmed/37895643 http://dx.doi.org/10.3390/ma16206661 |
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author | Chiesa, Irene Ceccarini, Maria Rachele Bittolo Bon, Silvia Codini, Michela Beccari, Tommaso Valentini, Luca De Maria, Carmelo |
author_facet | Chiesa, Irene Ceccarini, Maria Rachele Bittolo Bon, Silvia Codini, Michela Beccari, Tommaso Valentini, Luca De Maria, Carmelo |
author_sort | Chiesa, Irene |
collection | PubMed |
description | Four-dimensional (4D) printing is an innovative additive manufacturing technology used to fabricate structures that can evolve over time when exposed to a predefined environmental stimulus. 4D printed objects are no longer static objects but programmable active structures that accomplish their functions thanks to a change over time in their physical/chemical properties that usually displays macroscopically as a shapeshifting in response to an external stimulus. 4D printing is characterized by several entangled features (e.g., involved material(s), structure geometry, and applied stimulus entities) that need to be carefully coupled to obtain a favorable fabrication and a functioning structure. Overall, the integration of micro-/nanofabrication methods of biomaterials with nanomaterials represents a promising approach for the development of advanced materials. The ability to construct complex and multifunctional triggerable structures capable of being activated allows for the control of biomedical device activity, reducing the need for invasive interventions. Such advancements provide new tools to biomedical engineers and clinicians to design dynamically actuated implantable devices. In this context, the aim of this review is to demonstrate the potential of 4D printing as an enabling manufacturing technology to code the environmentally triggered physical evolution of structures and devices of biomedical interest. |
format | Online Article Text |
id | pubmed-10608699 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106086992023-10-28 4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications Chiesa, Irene Ceccarini, Maria Rachele Bittolo Bon, Silvia Codini, Michela Beccari, Tommaso Valentini, Luca De Maria, Carmelo Materials (Basel) Review Four-dimensional (4D) printing is an innovative additive manufacturing technology used to fabricate structures that can evolve over time when exposed to a predefined environmental stimulus. 4D printed objects are no longer static objects but programmable active structures that accomplish their functions thanks to a change over time in their physical/chemical properties that usually displays macroscopically as a shapeshifting in response to an external stimulus. 4D printing is characterized by several entangled features (e.g., involved material(s), structure geometry, and applied stimulus entities) that need to be carefully coupled to obtain a favorable fabrication and a functioning structure. Overall, the integration of micro-/nanofabrication methods of biomaterials with nanomaterials represents a promising approach for the development of advanced materials. The ability to construct complex and multifunctional triggerable structures capable of being activated allows for the control of biomedical device activity, reducing the need for invasive interventions. Such advancements provide new tools to biomedical engineers and clinicians to design dynamically actuated implantable devices. In this context, the aim of this review is to demonstrate the potential of 4D printing as an enabling manufacturing technology to code the environmentally triggered physical evolution of structures and devices of biomedical interest. MDPI 2023-10-12 /pmc/articles/PMC10608699/ /pubmed/37895643 http://dx.doi.org/10.3390/ma16206661 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chiesa, Irene Ceccarini, Maria Rachele Bittolo Bon, Silvia Codini, Michela Beccari, Tommaso Valentini, Luca De Maria, Carmelo 4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications |
title | 4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications |
title_full | 4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications |
title_fullStr | 4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications |
title_full_unstemmed | 4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications |
title_short | 4D Printing Shape-Morphing Hybrid Biomaterials for Advanced Bioengineering Applications |
title_sort | 4d printing shape-morphing hybrid biomaterials for advanced bioengineering applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608699/ https://www.ncbi.nlm.nih.gov/pubmed/37895643 http://dx.doi.org/10.3390/ma16206661 |
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