Cargando…

Utilizing a Combination of Network Pharmacology and Experimental Validation to Unravel the Mechanism by Which Kuanxiongzhuyu Decoction Ameliorates Myocardial Infarction Damage

Background and Objectives: With the growing incidence and disability associated with myocardial infarction (MI), there is an increasing focus on cardiac rehabilitation post-MI. Kuanxiongzhuyu decoction (KXZY), a traditional Chinese herbal formula, has been used in the rehabilitation of patients afte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yihao, Li, Miaofu, Chen, Liuying, Xu, Linhao, Xu, Yizhou, Zhong, Yigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10608708/ https://www.ncbi.nlm.nih.gov/pubmed/37893458 http://dx.doi.org/10.3390/medicina59101740

Ejemplares similares

Dangshen Erling Decoction Ameliorates Myocardial Hypertrophy via Inhibiting Myocardial Inflammation
por: Zhong, Yigang, et al.
Publicado: (2022)

Dissecting Chemical Composition and Cardioprotective Effects of Fuzhengkangfu Decoction against Doxorubicin-Induced Cardiotoxicity by LC–MS and Bioinformatics Approaches
por: Zhong, Yigang, et al.
Publicado: (2020)

Alterations in gut microbiota and host transcriptome of patients with coronary artery disease
por: Chen, Liuying, et al.
Publicado: (2023)

Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction
por: Zhao, Jiahao, et al.
Publicado: (2022)

Drug therapy for myocarditis induced by immune checkpoint inhibitors
por: Wu, Yihao, et al.
Publicado: (2023)

Modified Linggui Zhugan Decoction protects against ventricular remodeling through ameliorating mitochondrial damage in post-myocardial infarction rats
por: Xiang, Mi, et al.
Publicado: (2023)

TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation
por: Wu, Yirong, et al.
Publicado: (2023)

Suppression of CHOP Reduces Neuronal Apoptosis and Rescues Cognitive Impairment Induced by Intermittent Hypoxia by Inhibiting Bax and Bak Activation
por: Xu, Linhao, et al.
Publicado: (2021)

Systems Pharmacology Based Strategy for Q-Markers Discovery of HuangQin Decoction to Attenuate Intestinal Damage
por: Dai, Xiao-min, et al.
Publicado: (2018)

MicroRNAs as Biomarkers and Therapeutic Targets in Doxorubicin-Induced Cardiomyopathy: A Review
por: Chen, Liuying, et al.
Publicado: (2021)

Neutrophil Elastase Deficiency Ameliorates Myocardial Injury Post Myocardial Infarction in Mice
por: Ogura, Yukino, et al.
Publicado: (2021)

Unraveling the mechanism of tetrandrine combined with Buyang Huanwu Decoction against silicosis using network pharmacology and molecular docking analyses
por: Li, Yi, et al.
Publicado: (2023)

Uncovering the Pharmacology of Xiaochaihu Decoction in the Treatment of Acute Pancreatitis Based on the Network Pharmacology
por: Zhan, Lianghui, et al.
Publicado: (2021)

Pharmacologic treatment of depression in patients with myocardial infarction
por: Ha, Jeong-Hoon, et al.
Publicado: (2011)

Integration of summary data from GWAS and eQTL studies identified novel risk genes for coronary artery disease
por: Zhong, Yigang, et al.
Publicado: (2021)

Systems pharmacology dissection of pharmacological mechanisms of Xiaochaihu decoction against human coronavirus
por: Xu, Lvjie, et al.
Publicado: (2023)

The Herbal Formula Granule Prescription Mahuang Decoction Ameliorated Chronic Kidney Disease Which Was Associated with Restoration of Dysbiosis of Intestinal Microbiota in Rats
por: Ming, Yao, et al.
Publicado: (2021)

Network pharmacology to dissect the mechanisms of Yinlai Decoction for pneumonia
por: Xu, Jingnan, et al.
Publicado: (2020)

Effects of Buyang Huanwu Decoction on Ventricular Remodeling and Differential Protein Profile in a Rat Model of Myocardial Infarction
por: Zhou, Ying Chun, et al.
Publicado: (2012)

Traditional Chinese Medicine Shenmayizhi Decoction Ameliorates Memory and Cognitive Impairment Induced by Multiple Cerebral Infarctions
por: Sun, Chengcheng, et al.
Publicado: (2021)

Unraveling the Association Between Myocardial Infarction of Nonobstructive Coronary Arteries and Antiphospholipid Syndrome
por: Ramjas, Vishal, et al.
Publicado: (2021)

Local Injection of Hydroxyapatite Electret Ameliorated Infarct Size After Myocardial Infarction
por: Yamaguchi, Junji, et al.
Publicado: (2021)

Pharmacological Modulation of Cardiac Remodeling after Myocardial Infarction
por: Zhao, Wei, et al.
Publicado: (2020)

Metabonomic Profiles Delineate the Effect of Traditional Chinese Medicine Sini Decoction on Myocardial Infarction in Rats
por: Tan, Guangguo, et al.
Publicado: (2012)

Integrative genomic analysis identified common regulatory networks underlying the correlation between coronary artery disease and plasma lipid levels
por: Chen, Liuying, et al.
Publicado: (2019)

Anti-Myocardial Ischemia Reperfusion Injury Mechanism of Dried Ginger-Aconite Decoction Based on Network Pharmacology
por: Xie, Feng, et al.
Publicado: (2021)

Based on network pharmacology and in vitro experiments to prove the effective inhibition of myocardial fibrosis by Buyang Huanwu decoction
por: Wang, Tianyue, et al.
Publicado: (2022)

Constituents, Pharmacokinetics, and Pharmacology of Gegen-Qinlian Decoction
por: Lu, Jing-Ze, et al.
Publicado: (2021)

Linggui Zhugan Decoction activates the SIRT1-AMPK-PGC1α signaling pathway to improve mitochondrial and oxidative damage in rats with chronic heart failure caused by myocardial infarction
por: Yu, Siyi, et al.
Publicado: (2023)

Systematic Pharmacological Methodology to Explore the Pharmacological Mechanism of Siwu Decoction for Osteoporosis
por: Bao, Tingting, et al.
Publicado: (2019)

Which Coronary Lesions Are More Prone to Cause Acute Myocardial Infarction?
por: Sen, Taner, et al.
Publicado: (2017)

Hemorrhage promotes inflammation and myocardial damage following acute myocardial infarction
por: Pop, Mihaela, et al.
Publicado: (2014)

Effects of Yiqi Huoxue Decoction on Post-Myocardial Infarction Cardiac Nerve Remodeling and Cardiomyocyte Hypertrophy in Rats
por: Wang, Hui, et al.
Publicado: (2021)

Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode
por: Zhang, Guohua, et al.
Publicado: (2016)

A Network Pharmacology Approach to Uncover the Potential Mechanism of Yinchensini Decoction
por: Chen, Guoming, et al.
Publicado: (2018)

Erchen Decoction Ameliorates the Metabolic Abnormalities of High-Fat Diet-Fed Rats
por: Cheng, Ya, et al.
Publicado: (2022)

Protective effect of Qingre Huoxue decoction against myocardial infarction via PI3K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence
por: Jin, Zheng, et al.
Publicado: (2021)

Pharmacological Mechanism of Sancao Yuyang Decoction in the Treatment of Oral Mucositis Based on Network Pharmacology and Experimental Validation
por: Liu, Yunxia, et al.
Publicado: (2023)

Thrombospondin-1: A Key Protein That Induces Fibrosis in Diabetic Complications
por: Xu, Linhao, et al.
Publicado: (2020)

Deciphering the Pharmacological Mechanisms of Qidan Dihuang Decoction in Ameliorating Renal Fibrosis in Diabetic Nephropathy through Experimental Validation In Vitro and In Vivo
por: Liang, Qiuer, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b7ju5k119ndkunos8ps3ijvuri