New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity

A novel series of 1,2,3-triazole/1,2,4-triazole hybrids 5a, 5b, and 6a–i was designed and synthesized as antiproliferative agents targeting aromatase enzymes. The antiproliferative activity of the new hybrids against four cancer cells was studied using Erlotinib as a control. Compounds 6a and 6b dem...

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Detalles Bibliográficos
Autores principales: Maghraby, Mohamed T-E, Mazyad Almutairi, Tahani, Bräse, Stefan, Salem, Ola I. A., Youssif, Bahaa G. M., Sheha, Mahmoud M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609154/
https://www.ncbi.nlm.nih.gov/pubmed/37894571
http://dx.doi.org/10.3390/molecules28207092

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