Telacebec Interferes with Virulence Lipid Biosynthesis Protein Expression and Sensitizes to Other Antibiotics

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a public health issue, particularly due to multi-drug-resistant Mtb. The bacillus is wrapped in a waxy envelope containing lipids acting as essential virulence factors, accounting for the natural antibiotic resistance of mycobact...

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Detalles Bibliográficos
Autores principales: Zhou, Zhiyu, Wattiez, Ruddy, Constant, Patricia, Marrakchi, Hedia, Soetaert, Karine, Mathys, Vanessa, Fontaine, Véronique, Zeng, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609169/
https://www.ncbi.nlm.nih.gov/pubmed/37894127
http://dx.doi.org/10.3390/microorganisms11102469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609169/
https://www.ncbi.nlm.nih.gov/pubmed/37894127
http://dx.doi.org/10.3390/microorganisms11102469

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